tumoral calcinosis


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tu·mor·al cal·ci·no·sis

[MIM*114120]
1. calcification of collagen, chiefly at the site of large joints, in South African blacks; probably genetic.
2. calcinosis that develops in association with neoplastic conditions.

tumoral calcinosis

Oncology A condition characterized by single or multiple well-circumscribed calcium deposits in periarticular connective tissue, which may cause spinal cord compression and neurologic defects in mammals. See Calcinosis.
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Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis. Nat Genet 2004;36:579-581.
Spontaneous regression of multiple tumoral calcinosis in a child.
Ghosh, "Tumoral calcinosis," Indian Journal of Dermatology, Venereology and Leprology, vol.
This was considered to be consistent with Tumoral Calcinosis in the setting of long-standing renal disease.
Uraemic tumoral calcinosis is an uncommon occurrence in patients with chronic renal failure who are on long-term haemodialysis therapy, and falls within the broad definition of tumoral calcinosis.
Mutations in GALNT3, encoding a protein involved in 0-linked glycosylation, cause familial tumoral calcinosis. Nat Genet 2004;36:579-81.
Morphologically, the pseudogout lesions may resemble gout and other conditions, such as tumoral calcinosis.[5-7] Pseudogout crystals demonstrate diagnostic weak positive birefringence with polarizing microscopy in sections stained with the Shidham method.
These include myositis ossificans, lipomatous lesion, tumoral calcinosis, synovial sarcoma, and extraskeletal osteosarcoma, the most common being myositis ossificans.
TUMORAL CALCINOSIS: Definition: It is a distinct clinical and histologic entity that is characterized by tumor like peri articular deposits of calcium that are found mostly in the regions of hip, shoulder, and elbow.
Tumoral calcinosis may be defined as metastatic periarticular calcification that can be found in a wide variety of conditions such as primary hyperthyroidism and connective tissue diseases, as well as an idiopathic form.