tumor necrosis factor-alpha


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tumor necrosis factor-α

a pleiotropic cytokine synthesized widely throughout the female reproductive tract.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Analysis of nationwide databases in Denmark revealed that treatment with biologic agents (80% received tumor necrosis factor-alpha [TNF-[alpha]] inhibitors) or methotrexate was associated with lower CVD event rates over a mean follow-up of 18 months compared with patients given other antipsoriatic therapies.
Depression was more likely among participants who were female, lacked social support, had active disease, took corticosteroids but not tumor necrosis factor-alpha inhibitors, and showed less positive emotional recognition bias.
Nutritional states were evaluated by the measurements of body weight, body composition, and muscle strength, and the nutritional hematological examination results (retinol-binding protein (RBP), prealbumin (PA), transferrin (Tf), and hemoglobin (Hb) in serum), and inflammation biomarkers such as carboxyhemoglobin (COHb), High sensitivity C-reactive protein (Hs-CRP), Tumor Necrosis Factor-alpha (TNF-[alpha]), Interleukin 6 (IL-6), and Serum Amyloid A (SAA) were measured.
Neuroinflammation was lowered by EGCG via inhibition of MAPK and NF-kB pathways, in addition to decreased expression of the inflammatory mediator tumor necrosis factor-alpha.
Association of tumor necrosis factor-2 allele with plasma tumor necrosis factor-alpha levels and mortality from septic shock.
Role of tumor necrosis factor-alpha and interferon-gamma in Helicobacter pylori infection.
Tumor necrosis factor-alpha plays a role in the development of granulomatous diseases such as sarcoidosis.
(6) The disease is defined by increased expression of proinflammatory cytokines such as interleukin (IL)-1, IL-2, IL-6, IL-17, interferon-gamma (INF-[gamma]), and tumor necrosis factor-alpha (TNF-[alpha]).
Use of tumor necrosis factor-alpha inhibitors was associated with a significant reduction in the risk of coronary artery disease in patients with rheumatoid arthritis, particularly with longer term use of the drugs, in a retrospective cohort study.

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