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a tetrapeptide cleaved from IgG that stimulates phagocytosis by neutrophils. It is produced primarily in the spleen; hereditary tuftsin deficiency and tuftsin deficiency following splenectomy result in increased susceptibility to certain infections.
A tetrapeptide derived from the Fc region of an immunoglobulin. Tuftsin enhances macrophage functions.
[Tufts University + -in]
tuftsin/tuft·sin/ (tuft´sin) a tetrapeptide cleaved from IgG that stimulates phagocytosis by neutrophils.
a basic tetrapeptide produced in the spleen that stimulates phagocytosis in polymorphonuclear leukocytes and in macrophages.