tubulointerstitial

tubulointerstitial

(tū'yū-lō-in-tĕr),
Denotes all tubular and connective tissue elements of the kidney, not including the glomerulus.
References in periodicals archive ?
There, she was diagnosed with a rare genetic condition called autosomal dominant tubulointerstitial kidney disease (ADTKD).
14, 2019 (HealthDay News) -- A considerable proportion of families diagnosed at an autosomal dominant tubulointerstitial kidney disease specialist center are the result of direct family referral from the internet, according to a study published online July 24 in Genetics in Medicine.
So, the diagnosis of tubulointerstitial nephritis with mild mesangial sclerosis in association with PRES was given.
Among the 232 patients, who were over 50 years, the causes of CKD were identified as diabetic nephropathy (39.6%), hypertension (19.8%), renal stone disease (12.9%), tubulointerstitial disease (5.6%) and adult polycystic kidney disease (3%).
Glomerular proteinuria predicts the severity of acute kidney injury in Puumala hantavirus-induced tubulointerstitial nephritis.
In this study pathological changes in proximal tubules, interstitium and blood vessels are also observed culiminating to tubulointerstitial fibrosis.
Among the 232 patients, who were over 50 years, the causes of CKD were identified as diabetic nephropathy, hypertension, renal stone disease, tubulointerstitial disease and adult polycystic kidney disease.
To the Editor: Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease (ESRD); however, the onset of DKD is difficult to detect.[1] When persistent microalbuminuria becomes detectable, DKD has already progressed to the third disease stage, and finding biomarkers that are more sensitive than microalbuminuria is therefore necessary to indicate kidney damage at an earlier stage of DKD.[2] Both glomerular and tubulointerstitial damages have been repeatedly demonstrated to be important factors in the pathophysiology of DKD.[3] Therefore, we investigated the expression levels of six markers closely related to the glomerulus and renal tubule.
After 12 weeks, they examined both groups via biochemical and histological analyses and it was observed that experimental rats had lower plasma creatinine levels; less glomerulosclerosis, tubulointerstitial injury and extracellular matrix, and reduced thickening of basement membranes compared with controls.
Myofibroblast produces exaggerated extracelluer matrix (ECM), therefore, ECM accumulates in tubulointerstitial area [8].