Salivary glands are associated with exocrine tubuloalveolar
glands characterized by a cluster of multiple secretory units (Ozer, 2016).
The submucosa, which is denser than the lamina propria, contains mucous tubuloalveolar
esophageal glands proper.
and ductal architectural patterns as well as focal infiltration are commonly reported [2, 4, 7].
 intercommunicating tubuloalveolar
structure lined with two or more rows of cuboidal cells.
Diagnosis is based on histopathology, which shows nests of cuboidal or polygonal cells or intercommunicating tubuloalveolar
structures lined with two or more rows of cuboidal cells, ductal structures composed of one or two rows of cuboidal cells.
There were numerous nests of polygonal cells and interconnecting tubuloalveolar
structures lined by two layers of cuboidal epithelial cells (Fig.
Benign CMT present MMP-2 immunoreactivity in the myoepithelial cells lining the basement membrane of tubuloalveolar
structures, while malignant CMT showed mainly diffuse expression in neoplastic cells .
The tumors that arise from the head and neck region characteristically exhibit nests of cells with a lace-like stranding pattern of epithelial cells and tubuloalveolar
structures in a loose myxochondroid stroma, with a differentiation pattern of sweat glands and ducts.
Lactating adenomas are characterised by glands with a tubuloalveolar
architecture and florid secretory features.
Histologically, the tumors contain varying amounts of: nests of cuboidal/polygonal cells, tubuloalveolar
structures, ductal structures, keratinous cysts and matrix (chondroid substance is the most prevalent).
The shape of the secretory unit can be tubular, alveolar, or tubuloalveolar
(Fig ure 3-7).