tubulin binding agents

tubulin binding agents

a group of medications that bind tubulin and arrest cell mitosis. Abnormal blood vessels in tumors are particularly sensitive to these agents.
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In multiple Phase I trials in cancer patients, oral indibulin has been administered both as a single agent and in combination with favorable activity and a promising safety profile that does not include the neurotoxicity seen with all of the other classes of tubulin binding agents.
In multiple Phase I trials, oral indibulin has been administered both as a single agent and in combination with favorable activity, and has a promising safety profile that does not include the neurotoxicity seen with all of the other classes of tubulin binding agents.
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