TUBA1B

(redirected from tubulin alpha-1B chain)

TUBA1B

A gene on chromosome 12q13.12 that encodes an alpha tubulin, which combines with a beta tubulin to form microtubules, acting as a scaffold to determine cell shape and providing a matrix for cell organelle and vesicle movement via motor proteins.
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References in periodicals archive ?
The interacting proteins were those related to stress response (P14659), energetic metabolic process (ATP synthase subunit alpha, mitochondrial, P15999; ADP/ATP translocase 2, Q09073; ATP synthase subunit delta, mitochondrial, P35434 and citrate synthase, mitochondrial, Q8VHF5), microtubule constituent (tubulin alpha-1B chain, Q6P9V9), molecular functions (elongation factor 1-alpha 2, P62632; uncharacterized protein, F1M446; 14-3-3 protein theta, P68255; elongation factor 1-alpha 2, P62632), and cellular component (endoplasmic reticulum resident protein 29, P52555; 78kDa glucose-regulated protein, P06761) (Figure 6(b)).
In addition, proteins associated to stress response (heat shock cognate 71 kDa protein, P63018 and heat shock-related 70kDa protein 2, P14659) and microtubule constituent (tubulin alpha-1B chain, Q6P9V9) were clustered by ClusterMarker app.
In sublingual glands, we also found conjunctive constituent (collagen alpha-2(I) chain, P02466), cytoskeleton (Q5BJY9) and microtubule (tubulin alpha-1A chain, P68370; tubulin alpha-1B chain, Q6P9V9; and tubulin alpha-1C chain, Q6AYZ1) components uniquely in the nonexposed group.