TUBA1A

(redirected from tubulin alpha-1A chain)

TUBA1A

A gene on chromosome 12q13.12 that encodes an alpha tubulin, which combines with a beta tubulin to form microtubules, acting as a scaffold to determine cell shape and providing a matrix for cell organelle and vesicle movement via motor proteins.

Molecular pathology
Defects of TUBA1A cause of lissencephaly type 3.
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References in periodicals archive ?
In sublingual glands, we also found conjunctive constituent (collagen alpha-2(I) chain, P02466), cytoskeleton (Q5BJY9) and microtubule (tubulin alpha-1A chain, P68370; tubulin alpha-1B chain, Q6P9V9; and tubulin alpha-1C chain, Q6AYZ1) components uniquely in the nonexposed group.