tubulin


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Related to tubulin: alpha tubulin

tubulin

 [too´bu-lin]
the constituent protein of microtubules; thought to be involved in phagocyte motility.

tu·bu·lin

(tū'byū-lin),
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein.

tubulin

/tu·bu·lin/ (too´bu-lin) the constituent protein of microtubules.

tubulin

(to͞o′byə-lĭn, tyo͞o′-)
n.
A globular protein that is the basic structural constituent of microtubules.

tu·bu·lin

(tū'byū-lin)
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein

tubulin

A contractile protein that forms microtubules. These form the spindle fibres in MITOSIS that draw chromosomes apart is the course of cell division.

tubulin

a globular protein molecule, similar to ACTIN, that is the building block of microtubules within the cytoplasm of cells.

tubulin

the constituent protein of microtubules of cells which provide a skeleton for maintaining cell shape and is thought to be involved in cell motility.

α-tubulin
with β-tubulins contributes to the heterodimer tubulin, the building blocks of the electron microscopically visible cell components, the microtubules.
β-tubulin
one of the monomeric globular proteins which associate to form the dimer, α,β-tubulin, the basis of microfilaments.
References in periodicals archive ?
Thus, as previously we reported in one of our patients with Naxos disease, the enhanced automaticity of ectopic foci and/or reentry circuit around the scar tissue was abolished by cytoskeletal disruption mechanism, induced by tubulin destabilization with low-dose colchicines.
Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappa B and the serine/threonine kinase Akt and is independent of tubulin polymerization.
A common beta tubulin isotype-1 gene single nucleotide polymorphism as a tool for detection and quantitation of anthelmintic resistant Haemonchus contortus in grazing goats.
The localization of FMRFamide and tubulin immunoreactivity was best followed through a developmental sequence starting with the just-budded ephyra of Aurelia since the two stained subumbrellar networks showed very different relationships with the locomotory musculature in the early medusoid forms.
The tubulin gene family consists of six highly conserved sub-families including: alpha-; beta-; gamma-; delta-; epsilon- and zeta-tubulins (McKean et al.
Interestingly, [alpha]-TUB and [beta]-TUB are both tubulin genes, but the abundance of their proteins in the whole body or midgut samples were significantly different.
The doublet consists of A- and B-tubules: the A-tubules contain 13 tubulin protofilaments (A1-A13) and the B-tubules are incomplete tubules of 10 protofilaments (B1-B10).
The company intends to use the funds raised through the private placement to speed up its small molecule pipeline, especially late-stage registration studies of tesetaxel, an oral agent targetting tubulin in cancer cells that is currently in clinical development.
Tubulin is a globular (roughly spherical) protein that makes up microtubules in the cytoskeleton.
Sydney, Australia, June 16, 2010 - (ABN Newswire) - Benitec Limited (ASX:BLT) (PINK:BNIKF) are pleased to announce the publication of a paper in the prestigious scientific journal Cancer Research by Associate Professor Maria Kavallaris from Children's Cancer Institute Australia for Medical Research (CCIA) and the University of New South Wales (UNSW), relating to the association between beta tubulin and chemotherapy resistance in cancers.