NGAL, a member of the lipocalin family, is secreted from kidney proximal tubuli
after ischemic damage.
Renal tissue samples were analysed blindly, by a histologist working in the Dokuz Eylul University Medical Faculty Histology Department, under a light microscope with regard to the structural changes of proximal tubuli
(tubular atrophy, tubular brush border loss, tubular dilatation, cast formation, vacuolization), mononuclear cell (MNL) infiltration, erythrocyte extravasation and structural changes of interstitial space.
Debemos valorar que estas cisternas podian estar destinadas no solo a la recogida de agua de lluvia, sino tambien al almacenaje del agua procedente del propio acueducto a traves de tubuli
o fistulae de plomo.
Lipophilic drugs are reabsorbed from the tubuli
upon the concentration of the primary urine.
In kidney, the apical sodium dependent transporter (ASBT) is downregulated in proximal renal tubuli
causing a reduced reabsorption and an increased BA urinary excretion .
Kratzsch, "Leptin exists in tubuli
seminiferi and in seminal plasma," Andrologia, vol.
The most vastly distributed protein within this family is CEACAM1, being expressed on various normal epithelia from the gastrointestinal tract (intestinal and colonic superficial epithelial cells, duodenal Brunner glands, esophageal glands, bile, and pancreatic ducts), prostatic glands, gall bladder, mammary ducts, endometrium, renal tubuli
, extravillous trophoblast, etc., as well as endothelial cells, natural killer (NK) cells, T and B lymphocytes, and myeloid cells [3-9].
Light microscopy observation of kidney tissues in control rats showed regular renal parenchyma with glomeruli and tubuli
In eyes with development of untreatable retinal tubuli
or fibrotic scar, or BCVA < 20 ETDRS letters with a dry macula, treatment was stopped.
Figure 7(a) shows one of the irregular dentine fragments, clearly identifiable by the presence of dentinal tubuli
. The dentine fragments were present throughout the sample.
In kidney tissue sections of control rats, a normal structure of glomeruli as well as proximal and distal tubuli
was observed (Figures 2(a) and 2(b)).
A portion of the glycotoxins filtered in the glomeruli are disintegrated in the tubuli
and the remainder is excreted in urine.