tubular secretion

tubular secretion

The passage of unneeded substances from the peritubular capillaries into the tubule of the nephron and hence into the urine.
References in periodicals archive ?
It is eliminated unchanged from the body by renal tubular secretion and glomerular filtration.
Unlike Cr, which undergoes proximal tubular secretion in addition to filtration, CysC is freely filtered in the glomerulus and >99% is reabsorbed and catabolized in proximal tubular cells.
However, it has become evident that the creatinine concentration is far from ideal because it is significantly changed by other factors such as muscle mass, diet, gender, age and tubular secretion.
Many drugs and their metabolites are excreted by the kidney by glomerular filtration, by tubular secretion, or in some cases by both.
The Icahn/Mount Sinai team reminds colleagues that drugs affecting tubular secretion of creatinine also sway creatinine-based kidney function estimates.
In this aspect, the kidney performs three basic functions: glomerular filtration, tubular reabsorption, and tubular secretion.
First, creatinine excreted in the urine is not solely a result of glomerular filtration but also a result of renal tubular secretion [12].
The kidneys' handling of drugs occurs through three processes: glomerular filtration, tubular reabsorption and tubular secretion.
52% of the excreted PAH originated from the tubular secretion of control and exhausted animals, respectively (Figure 3).
Acidic mucins, neutral lipids, glycolipids and phospholipids were normal components of the tubular secretion.
Dronedarone interferes with the tubular secretion of creatinine, which produced a 5% increase in blood levels of creatinine, compared with a 1% increase on placebo.
These factors include tubular secretion, generation, and extra-renal excretion of creatinine as well as older age, gender, diet, body habitus, and certain medications such as trimethoprim, cimetidine, and fibric acid derivatives (other than gemfibrizil) which increase the serum creatinine by reducing its tubular secretion.