tubular proteinuria


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Related to tubular proteinuria: glomerular proteinuria

proteinuria

 [pro″te-nu´re-ah]
an excess of serum proteins in the urine, such as in renal disease, after strenuous exercise, or in dehydration.
accidental proteinuria (adventitious proteinuria) proteinuria due not to a kidney disease but to some other condition such as hemorrhage in the urinary tract; called also false proteinuria.
athletic proteinuria effort proteinuria.
dietetic proteinuria (digestive proteinuria) functional proteinuria produced by the eating of certain foods.
effort proteinuria functional proteinuria occurring as a result of vigorous and prolonged exercise of the lower limbs; called also athletic proteinuria.
false proteinuria adventitious proteinuria.
functional proteinuria any proteinuria that is not due to renal disease, such as the transient proteinuria of pregnancy, effort proteinuria, and orthostatic proteinuria.
glomerular proteinuria the most common kind of proteinuria, being due to glomerular disease and abnormal permeability of the glomerular capillaries to protein.
orthostatic proteinuria a form of functional proteinuria, usually seen between the ages of ten and twenty, that occurs on standing erect and disappears on lying down.
overflow proteinuria that due to hemoglobin, myoglobin, or immunoglobulin loss into the urine due to excessive amounts in the bloodstream, such as in multiple myeloma; it is not usually associated with glomerular or tubular disease.
tubular proteinuria proteinuria due to excretion of proteins of low molecular weight such as immunoglobulins, which normally should be reabsorbed.

tubular proteinuria

The loss of relatively small amino acids, immunoglobulin light chains, and other small proteins (less than 25 kD) in the urine, because of failure of the renal tubules to reabsorb proteins that have been filtered by the glomerulus.
See also: proteinuria

tubular

1. pertaining to renal tubules.
2. pertaining to fallopian tube.

tubular backleak
leakage of tubular fluid into the interstitium of the kidney is one of the factors in the pathogenesis of acute renal failure.
tubular maxima
the concentrations of solutes at which the renal tubules are working at full capacity and further increases in concentration will not increase the function. Called also Tm.
tubular necrosis
acute necrosis of the tubular epithelium caused usually by ischemia or exposure to a nephrotoxin; in most cases the patient succumbs to uremia in a few days. See also nephrosis.
tubular proteinuria
failure of the tubules to resorb small molecule proteins excreted by the glomerulus.
tubular reabsorption
reabsorption of solutes from the glomerular filtrate by the tubules, the conservation of protein, glucose and bicarbonate, and the conservation of the water that accompanies them.
tubular transport
refers to all processes which occur with renal tubular fluid during its transport from glomerular space to renal pelvis.
tubular transport maximum
when the tubular transport maximum for a renal tubular solute is exceeded the solute appears in the urine.
References in periodicals archive ?
However it is obvious that the more serious nature of bone effects compared with a slight tubular proteinuria should be considered in the health risk assessment.
Current information urges a shift in the strategy for assessment of Cd risks in the general population, moving away from a unique focus on renal tubular proteinuria.
Cadmium and lead in blood in relation to low bone mineral density and tubular proteinuria.
below 20 [micro]g/g cr) 1,000-10,000 Irreversible tubular proteinuria that may accelerate the decline of glomerular filtration rate with age.
During the past decade, several studies have shown that urinary cadmium concentrations of 2-4 nmol/mmol creatinine are associated with tubular proteinuria in both occupationally and environmentally exposed populations (Jarup et al.
The cut-off points used for tubular proteinuria were 0.
Figure 1 shows the odds ratios (with 95% CIs) for tubular proteinuria for different blood cadmium groups in the environmentally exposed group, after adjustment for age, sex, and smoking.
Our results show that there is a relationship between blood cadmium and tubular proteinuria and low bone mineral density.
It has been shown that blood cadmium can be a better dose estimate when tubular proteinuria is present (27).
It's also interesting to note that even 15 years after the cessation of exposure, cadmium-exposed workers showed a stronger association between blood cadmium and tubular proteinuria than between urinary cadmium and tubular proteinuria, implying that there may be a dose--response relationship involved.
Rapid differentiation of glomerular and tubular proteinuria by sodium dodecyl sulfate polyacrylamide gel electrophoresis.
Reversible tubular proteinuria precedes microalbuminuria and correlates with the metabolic status in diabetic children.