MALIGNANT LESIONS: Out of the 50 cases diagnosed as malignant lesions, 38 cases were diagnosed as invasive ductal carcinoma, 5 cases as mucinous carcinoma, 2 invasive lobular carcinoma and 1 case each of CA breast, comedo carcinoma, medullary carcinoma, papillary carcinoma and tubular carcinoma
Tumours are small in size than IDC but similar to tubular carcinoma
ranging from 0.
Malignant (18%; 31/177) Invasive ductal carcinoma 13 Invasive lobular carcinoma 4 Ductal carcinoma in situ 12 Invasive mixed carcinoma 1 Tubular carcinoma
1 Atypical epithelial hyperplasia (11%; 20/177) Atypical ductal hyperplasia 3 Lobular neoplasia 17 (12 ALH, 5 LCIS) Benign (71%;126/177) Benign breast diagnoses (105/126) Fibrocystic changes with/without 31 epithelial hyperplasia Columnar cell lesions 30 Fibroadenoma and 14 fibroadenomatoid change Ductal ectasia 7 Radial sclerosing lesion 6 Papilloma 7 PASH 5 Intramammary lymph node 3 Fat necrosis 1 Hemangioma 1 Normal breast tissue (21/126) Abbreviations: ALH, atypical lobular hyperplasia; LCIS, lobular carcinoma in situ;PASH, pseudoangiomatous stromal hyperplasia.
Microglandular adenosis of the breast--a lesion simulating tubular carcinoma
An adenosis and pseudo infiltrative pattern were also prominent in the present case, and resembled invasive tubular carcinoma
or adenosquamous carcinoma.
3) 0 (0) Mixed ductal and mucinous carcinoma (N = 6) Grade 1 0 (0) 2 (100) 0 (0) Grade 2 2 (50) 2 (50) 0 (0) Tubular carcinoma
(N = 2) Grade 1 1 (50) 1 (50) 0 (0) Invasive carcinoma with micropapillary component (N = 15) Grade 2 10 (76.
4-10) It was actually first recognized by Japanese investigators in the mid 1990s and then was proposed to be named intraductal tubular carcinoma
by the Japan Pancreas Society in 2002.
Microglandular adenosis, apocrine adenosis, and tubular carcinoma
of the breast: an immunohistochemical comparison.
MYOEPITHELIAL-NEGATIVE SMALL GLANDULAR PROLIFERATIONS--MGA AND TUBULAR CARCINOMA
It is characterized by positive S100, negative estrogen receptor (ER), and negative progesterone receptor (PR) immunohistochemical stains and positive basement membrane stains such as collagen type IV and laminin, contrasting with tubular carcinoma
, for which it is often mistaken.
20) Many subtypes of invasive breast cancer, such as invasive tubular carcinoma
(ITC), medullary carcinoma (MC), and invasive mucinous carcinoma (IMC), have traditionally been considered to be associated with a more favorable prognosis, while others such as invasive micropapillary carcinoma have been thought to be associated with a poor outcome.
An associated invasive tubular carcinoma
is often present.