tubocurarine


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tubocurarine

 [too″bo-ku-rah´rēn]
an alkaloid from the bark and stems of Chondrodendron tomentosum; it is the active principle of curare and is a nondepolarizing neuromuscular blocking agent; used in the form of the chloride salt for relaxation of skeletal muscles in surgery and convulsive therapy and as an aid in the diagnosis of myasthenia gravis. Administered intravenously or intramuscularly.

tubocurarine

/tu·bo·cu·ra·rine/ (-ku-rah´rēn) an alkaloid from the bark and stems of Chondrodendron tomentosum; it is the active principle of curare and is a nondepolarizing neuromuscular blocking agent; used as the chloride salt as a skeletal muscle relaxant and as an aid in the diagnosis of myasthenia gravis.

tubocurarine

(to͞o′bō-ko͝o-rä′rĭn, -rēn′, -kyo͝o-, tyo͞o′-)
n.
1. An alkaloid that is an active component of curare obtained from the plant Chondrodendron tomentosum.
2. The hydrated chloride form of this alkaloid, C38H44Cl2N2O6, used as a drug to relax skeletal muscles during anesthesia.

tubocurarine

an alkaloid from the bark and stems of Chondrodendron tomentosum. d-tubocurarine chloride is used as a skeletal muscle relaxant.
References in periodicals archive ?
Diaphragm contractions induced by phrenic nerve stimulation were fully inhibited by tubocurarine in a concentration-dependent manner ([IC.
The effects of tubocurarine elicited train of four muscle response and repiratory measurements in humans, Br J Anaesth 1975; 47: 570-573.
To name only a few of the important drugs in use today, aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine serve as examples (Gilani, A.
Comparison of tubocurarine and pancuronium in nitrous oxide and oxygen.
Of the various pharmaceuticals used in modern medicine, aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine serve as examples of drugs discovered through observations of indigenous medical practices (Gilani, A.
Important modern drugs that have been derived from observations of traditional curing methods of indigenous people include aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine (Gilani, A.
Tubocurarine was the drug of choice for operations of any significant duration, but because tubocurarine lasted around thirty minutes, gallamine was often preferred for shorter operations.
Modern drugs like aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine serve as examples, which were originally discovered through observations of traditional cure methods of indigenous peoples (Gilani, A.
Even in recent times, plants have been an important source of modern drugs like aspirin, ephedrine, digoxin, quinine and tubocurarine, to name only a few (Gilani, 2005).