Corticosteroids have been used as therapy for a number of infectious diseases, and steroid use has been shown to improve survival in patients with bacterial meningitis, tuberculous meningitis, tuberculous pericarditis
, severe typhoid fever, tetanus, or Pneumocystis pneumonia with moderate to severe hypoxemia.
In this case, Tuberculous pericarditis
was present as a thickening of the pericardium with pericardial effusion.
Through his investigation of tuberculosis in the heart, he clarified the appropriate diagnostic strategy and role of adjunctive steroids in tuberculous pericarditis
. He showed that unstimulated interferon gamma is the most sensitive and specific screening test for tuberculous pericarditis
In contrast to pericarditis reports from other countries, none of our patients was diagnosed with tuberculous pericarditis
A case of tuberculous pericarditis
. Br Heart J 1944;6(4):185-90.
Adenosine deaminase activity in tuberculous pericarditis
. Thorax 1986; 41: 888.
However, histopathology was consistent with acute suppurative pericarditis on top of chronic granulomatous inflammation with Langhans-type giant cells and caseation necrosis, indicative of tuberculous pericarditis
with superimposed bacterial pericarditis.
A preliminary diagnosis of tuberculous pericarditis
and cardiac tamponade was made, and the patient was administered an antitubercular treatment consisting of isoniazid, rifampicin, pyrazinamide, and ethambutol, in addition to oral prednisone.
 Most reports cite pulmonary hypertension, cardiomyopathy and tuberculous pericarditis
as the predominant HIV-related cardiovascular conditions.
Larrieu AJ, Tyers GF, Williams EH, Derrick JR.Recent experience with tuberculous pericarditis
. Ann Thorac Surg 1980; 29: 464-8.
([double dagger]) Tuberculous meningitis, tuberculous pericarditis
, disseminated tuberculosis, pulmonary tuberculosis.