40] Prednisone is not recommended for tuberculous pericarditis
in HIV, as it conferred no survival benefit and was associated with an increased risk of HIV-related malignancies in an RCT.
double dagger]) Tuberculous meningitis, tuberculous pericarditis
, disseminated tuberculosis, pulmonary tuberculosis.
Management of tuberculous pericarditis
and tuberculous pericardial effusion in Transkei: results at 10 year follow-up.
Although Africa is seeing a rise in lifestyle-associated atherosclerosis and other conditions common in the developed world, there are also large numbers of people suffering from chronic heart conditions with infectious origins, including rheumatic heart disease arising from streptococcal infection, endomyocardial fibrosis, and tuberculous pericarditis
As tuberculous pericarditis
is by far the most common cause of an effusion in this setting, patients with a pericardial effusion >5 mm in width were started on treatment for TB and closely monitored.
Since that time there has been much debate over whether "primary" tuberculous pericarditis
is a separate clinicopathologic entity or whether it is the recognizable result of an earlier resolved or inactive primary lesion.
SAN FRANCISCO -- Adjunctive prednisolone works better than placebo in HIV-positive patients being treated for tuberculous pericarditis
, based on the results of a randomized, controlled trial.
A local study on patients with pericardial effusions of 10 mm or more in size found that tuberculous pericarditis
was present in 53%, 100% had an enlarged cardiothoracic ratio, and 45.
In contrast to tuberculous pericarditis
, the myocardium is resistant to inflammation but can rarely present with tuberculomas.
In this issue of SAMJ, Mayosi and colleagues (1) report the results of an observational study on the mortality rate and its predictors in patients with a presumptive diagnosis of tuberculous pericarditis
in sub-Saharan Africa.
To determine the mortality rate and its predictors in patients with a presumptive diagnosis of tuberculous pericarditis
in sub-Saharan Africa.
In a groundbreaking research model for Africa, Mayosi and colleagues (2) enrolled patients with presumed tuberculous pericarditis
from 15 referral hospitals in Cameroon, Nigeria and South Africa.