tuberculoid leprosy


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tu·ber·cu·loid lep·ro·sy

a benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges.

tuberculoid leprosy

See leprosy.

tu·ber·cu·loid lep·ro·sy

(tū-bĕr'kyū-loyd lep'rŏ-sē)
A benign, stable, and resistant form of leprosy in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with distinct edges.
Synonym(s): nodular leprosy.

tuberculoid leprosy

presentation of Hansen's disease, see Table 1
Table 1: Presentations of Hansen's disease (leprosy)
Leprosy typeCharacteristics
Tuberculoid leprosy (TT) or paucibacillary leprosy (PB)Vigorous host resistance and low infection
A localized disease in patients with high cell-mediated immunity characterized by a single, clearly demarcated hypopigmented anaesthetic skin area of the face, hands or feet, with thickening of the subserving nerve
Borderline tuberculoid leprosy (BT)As TT, but more numerous, smaller skin lesions with thickening of peripheral nerves and deformity of the hands and feet
Borderline leprosy (BB)Numerous skin lesions of varying size and form (macules, papules, plaques) with punched-out, hypopigmented anaesthetic centres; widespread nerve involvement and limb deformity
Borderline lepromatous leprosy (BL)Large number of florid asymmetrical skin lesions of variable form, strongly positive to acid-fast bacilli
Lepromatous leprosy (LL) or multibacillary leprosy (MB)Severely compromised host resistance and massive infection Skin changes of the face, earlobes, buttocks, upper and lower limbs, peripheral oedema, rhinitis and loss of the outer one-third of the eyebrows are characteristic of the early stages, with later mucous membrane involvement causing nasal stuffiness, laryngitis and hoarseness, thence nasal septum perforation and collapse of the nasal cartilages (saddle-nose deformity), glove-and-stocking anaesthesia, gynaecomastia, testicular atrophy, ichthyosis, nerve palsies and neurotrophic resorption of the phalanges. Lucio's phenomenon (endarteritis and ulceration) is noted in Mexico and Central America
References in periodicals archive ?
Borderline tuberculoid was the most common type histologically followed by tuberculoid leprosy.
Borderline tuberculoid leprosy coexisting with systemic lupus erythematosus.
Patients with tuberculoid leprosy mount a cellmediated immune response that will result in a positive lepromin test.
4,9) Tuberculoid leprosy also reflects a sufficient cell-mediated immune response, but these patients have one or two hypopigmented, erythematous, and anesthetic macules with a raised margin.
It looked as if we had converted that limited area from lepromatous to tuberculoid leprosy," Nathan says.
Case 2: A 23 year-old, mulatto man with a two-year history of prednisone treatment for bouts of nodules appearing over a macula who had been on treatment for tuberculoid leprosy with MDT-PB.
Report of two AIDS patients presenting a shifting from borderline lepromatous leprosy to borderline tuberculoid leprosy.
2) Though nerve abscesses are rare in lepromatous leprosy due to low cell mediated immunity, multiple nerve abscesses are more common in lepromatous leprosy than in tuberculoid leprosy.
Macular lesions or plaques 1 to 3 in number with welldefined margins, dry, rough, irregular surface associated with anaesthesia and thickened nerves were labelled as tuberculoid leprosy.
A biopsy was done from the skin lesion and subjected to histopathological examination which revealed features of borderline tuberculoid leprosy, in type 1 lepra reaction (Figure 2).
described the first case of IRIS after the onset of HAART in a patient who had tuberculoid leprosy that was never confirmed by molecular analysis (3).
I read with interest the case report "Autochthonous borderline tuberculoid leprosy in a man from Florida" by Villada, et al.