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Trp; a naturally occurring amino acid, existing in proteins. High levels of intake of d,l-tryptophan are thought to be a significant cause of atypical interstitial pneumonia in cattle. The actual toxic agent is 3-methylindole, a metabolic product of d,l-tryptophan in the rumen.
component of some roughages; high levels can cause acute bovine pulmonary emphysema and edema.
first enzyme in the catabolic pathway for tryptophan. Essential step in the pathway to synthesis of nicotinamide nucleotides NAD+ and NADP+. Approximately 30% of the nicotinamide nucleotide requirement of some animals can be supplied through this enzyme. The cat is notably lacking in the latter capacity.