eosinophilia-myalgia syndrome

(redirected from tryptophan-induced)

eosinophilia-myalgia syndrome

 
a sometimes fatal syndrome of severe myalgia associated with marked peripheral eosinophilia, associated with the ingestion of oral preparations of l-tryptophan; long-term sequelae include scleroderma and progressive neuropathy.

e·o·sin·o·phil·i·a-·my·al·gi·a syn·drome (EMS),

a probable autoimmune disorder precipitated by contaminated l-tryptophan tablets; characterized by fatigue, low-grade fever, myalgias, muscle tenderness and cramps, weakness, paresthesias of the extremities, and skin indurations; marked eosinophilia is noted on peripheral blood studies, serum aldolase is increased, and biopsies of peripheral nerve, muscle, skin, and fascia show microangiopathy and inflammation in connective tissue.
Synonym(s): E-M syndrome

e·o·sin·o·phil·i·a-my·al·gi·a syn·drome

(ē'ō-sin-ō-fil'ē-ă mī-al'jē-ă sin'drōm)
A probable autoimmune disorder precipitated by ingestion of contaminated l-tryptophan tablets, and characterized by fatigue, low-grade fever, myalgias, muscle tenderness and cramps, weakness, paresthesias of the extremities, and skin indurations; marked eosinophilia is noted on peripheral blood studies; serum aldolase is increased and biopsies of peripheral nerve, muscle, skin, and fascia show microangiopathy and inflammation in connective tissue.

eosinophilia-myalgia syndrome

A disorder featuring severe and persistent pain in the muscles, muscle weakness, loss of weight, fever, ‘pins and needles’ sensation (paraesthesia) and an exceptionally high level of EOSINOPHIL white cells in the blood. The cause is unknown but there is a strong association with ingestion of L-tryptophan.
References in periodicals archive ?
Whether your dinner conversation slows to a tryptophan-induced crawl or you need to distract your family from high-tension debates over dessert, here are five conversation prompts to keep the dialog flowing this Thanksgiving.
As they wait to see how these factors shake out, sales brokers are sleeping off their post-Thanksgiving, tryptophan-induced hang overs, and settling in to what is, between the chilly weather and the string of holidays, typically the slowest season of the year.
I sacked out too, but it wasn't tryptophan-induced. I just feel rotten.
Leave some goods and gift items on the shelves for the rest of us who, perhaps because of tryptophan-induced tiredness, opened one eye at 3 or 4 this morning, saw how black it was behind the bedroom curtains, and chose to snooze, instead.