eosinophilia-myalgia syndrome

(redirected from tryptophan-induced)

eosinophilia-myalgia syndrome

 
a sometimes fatal syndrome of severe myalgia associated with marked peripheral eosinophilia, associated with the ingestion of oral preparations of l-tryptophan; long-term sequelae include scleroderma and progressive neuropathy.

e·o·sin·o·phil·i·a-·my·al·gi·a syn·drome (EMS),

a probable autoimmune disorder precipitated by contaminated l-tryptophan tablets; characterized by fatigue, low-grade fever, myalgias, muscle tenderness and cramps, weakness, paresthesias of the extremities, and skin indurations; marked eosinophilia is noted on peripheral blood studies, serum aldolase is increased, and biopsies of peripheral nerve, muscle, skin, and fascia show microangiopathy and inflammation in connective tissue.
Synonym(s): E-M syndrome

eosinophilia-myalgia syndrome, tryptophan-induced

a potentially fatal disorder resulting from ingestion of tryptophan. It is characterized by a symptom complex of severe muscle pain, tenosynovitis, muscle edema, and skin rash lasting several weeks.

e·o·sin·o·phil·i·a-my·al·gi·a syn·drome

(ē'ō-sin-ō-fil'ē-ă mī-al'jē-ă sin'drōm)
A probable autoimmune disorder precipitated by ingestion of contaminated l-tryptophan tablets, and characterized by fatigue, low-grade fever, myalgias, muscle tenderness and cramps, weakness, paresthesias of the extremities, and skin indurations; marked eosinophilia is noted on peripheral blood studies; serum aldolase is increased and biopsies of peripheral nerve, muscle, skin, and fascia show microangiopathy and inflammation in connective tissue.

eosinophilia-myalgia syndrome

A disorder featuring severe and persistent pain in the muscles, muscle weakness, loss of weight, fever, ‘pins and needles’ sensation (paraesthesia) and an exceptionally high level of EOSINOPHIL white cells in the blood. The cause is unknown but there is a strong association with ingestion of L-tryptophan.
References in periodicals archive ?
As they wait to see how these factors shake out, sales brokers are sleeping off their post-Thanksgiving, tryptophan-induced hang overs, and settling in to what is, between the chilly weather and the string of holidays, typically the slowest season of the year.
Leave some goods and gift items on the shelves for the rest of us who, perhaps because of tryptophan-induced tiredness, opened one eye at 3 or 4 this morning, saw how black it was behind the bedroom curtains, and chose to snooze, instead.
Tryptophan-induced A retained risk; plan drowsiness ahead for good spot in front of TV.
LEWISVILLE, Texas -- As Thanksgiving dissolves into a tryptophan-induced haze, your thoughts may well turn to Christmas; or more accurately, the holiday chore of dragging the Christmas decorations out of storage--be it down from the attic, or out of the closet, or in from the garage, or from whatever space it is that you stash them for the 330-plus days that they are not making your home more merry.
This potentially tryptophan-induced surge has dropped the stock's Schaeffer's put/call open interest ratio (SOIR) from Friday's reading of 0.