trypsin inhibitor

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Related to trypsin inhibitor: pancreatic trypsin inhibitor

tryp·sin in·hib·i·tor

1. a peptide formed from trypsinogen through hydrolysis under the catalytic influence of enteropeptidase, with trypsin also produced as a result; so called because the peptide masks or inhibits the active site of the trypsin molecule;
2. one of the polypeptides, from various sources (for example, human and bovine colostrum, soybeans, egg white), that inhibit the action of trypsin. Compare: Bowman-Birk inhibitor.

trypsin inhibitor

one of a group of peptides, present in such varied sources as soybeans, egg white, and human colostrum, that mask or inhibit the active site of the trypsin molecule. Also called kunitz inhibitor.


a proteolytic enzyme formed in the intestine by the cleavage of trypsinogen by enterokinase. Trypsinogen enters the intestine as part of the intestinal juice. It is an endopeptidase that hydrolyzes peptides of arginine or lysine.

trypsin fecal tests
see fecal trypsin.
feline trypsin-like immunoreactivity (fTLI)
see trypsin-like immunoreactivity (below).
trypsin inhibitor
small protein synthesized in the exocrine pancreas which prevents conversion of trypsinogen to trypsin, so protecting itself against trypsin digestion. Pancreatic trypsin inhibitor competitively binds to the active site of trypsin and inactivates it at a very low concentration. The binding is amongst the strongest noncovalent associations, but only a fraction of the potential trypsin is so inhibited.
trypsin-like immunoreactivity (TLI)
serum proteins, particularly trypsinogen, react immunologically as trypsin and a normal level is dependent upon a normally functional pancreas. This is used in the diagnosis of exocrine pancreatic insufficiency.
References in periodicals archive ?
Determination of trypsin inhibitor activity of soy products: a collaborative analysis of an improved procedure.
JOHNSEN (1999): <<A Kazal-type trypsin inhibitor from the protochordate Ciona intestinalis>>, European Journal of Biochemistry, vol.
Additional evidence for the trypsin identity of isolated enzymes was obtained by the use of inhibitors, since all enzymes were affected by serine-proteinase and trypsin inhibitors (Table 2).
Although trypsin inhibitor activity has been partially or fully inactivated by different treatments (18) and the inactivation process might be attributed to formation of high molecular weight aggregated among trypsin inhibitor and others proteins, (7,8) beans nutritional value have been improved by thermal inactivation treatment, (8,11,18) highpressure, (31) extrusion cooking, (21) natural fermentation, (15) pressure-cooking (121[degrees]C.
Cyanide content, tannin content, oxalate content, trypsin inhibitor activity and haemagglutanin activity of oil seeds under study are given in Table 1.
2003, "Effect of soaking, dehulling, cooking and fermentation with Rhizopus oligosporus on the oligosaccharides, trypsin inhibitor, phytic acid and tannins of soybean (Glycine max Merr.
It has launched a broad-acting trypsin inhibitor, used in sepsis and multiple organ dysfunctions treatment.
The ingredient called pancreatic secretory trypsin inhibitor, or PSTI, is found at its highest levels in colostrum - the milk produced in the first few days after birth.
Electrophoretic separation and properties of winged bean seed trypsin inhibitor.
During the sprouting period, starch content decreased; reducing and non-reducing sugars increased; tannins, trypsin inhibitor and phytates decreased; and in-vitro digestibility increased.
Aprotinin (2 trypsin inhibitor units/mL) was added to each blood sample; the blood was then centrifuged at 15,000 rpm, and the supernatant was removed and fiozen on dry ice for transportation and subsequently stored at -20[degrees]C.