trypomastigote

tryp·o·mas·ti·gote

(trip'ō-mas'ti-gōt),
Term to replace the older term, "trypanosome stage," which was often confused with the flagellate genus Trypanosoma. It denotes the stage (ineffective stage for South American trypanosomiasis and African trypanosomiasis, and the only stage found in humans in the latter illness) in which the flagellum arises from a posteriorly located kinetoplast and emerges from the side of the body, with an undulating membrane running along the length of the body.
[G. trypanon, auger, + mastix, whip]

trypomastigote

(trip″ŏ-mas′ti-gōt″) [fr. tryp(anosome) + mastigote]
Any of the circulating forms of the protozoan parasite, Trypanosomacruzi. They swim and feed in the blood and may be transmitted from person to person (e.g. in blood transfusions) or from mother to developing fetus across the placenta.
References in periodicals archive ?
Albuquerque, In vitro activity of Rutaceae species against the trypomastigote form of Trypanosoma cruz', Journal of Ethnopharmacology, 73(1- 2),335-340 (2000)
The bloodstream trypomastigote form of the parasite was maintained in Swiss mice by serial passage of infected blood (11).
Taking into account the different motifs identified in the LYT1 UTRs and the roles played in other organisms, it can be hypothesized the following regulatory model: The Sxl element would have a positive regulation on the mLYTl transcript in the trypomastigote stage whereas at the epimastigote stage this transcript would be down regulated by the G rich motif.
Leyenda: Figura 1: A: Imagen microscopica del microstrout en donde es posible visualizar un trypomastigote metaciclico de Trypanosoma Cruzi senalado por la flecha.
During its life cycle, this parasite undergoes major changes in the kinetoplast morphology and kDNA topology as it passes from the epimastigote replicative stage in the insect vector to the metacyclic trypomastigote form, which infects humans, in a process known as metacyclogenesis.
Infections were performed using trypomastigote forms obtained at peak of parasitemia from previously infected Swiss mice (Waynforth and Flecknell, 1992).
Sanchez, "Identification of novel vaccine candidates for Chagas' disease by immunization with sequential fractions of a trypomastigote cDNA expression library," Vaccine, vol.
Rosestolato, C.T., Dutra, J, M., De Souza, W., de Carvalho, T.M (2002) Participation of host cell actin filaments during interaction of trypomastigote forms of Trypanosoma cruzi with host cells.
Although there is controversy among authors regarding the use of epimastigotes for these trials, it is important to note that previous studies demonstrated a correlation between epimastigote, trypomastigote, and amastigote forms of T.
An enzyme immunoassay was reactive and an immunoblot of trypomastigote excreted-secreted antigens was positive, confirming the diagnosis.
During week 29, routine monitoring was reinitiated and the patient tested positive by PCR, hemoculture, and serology (trypomastigote excreted-secreted antigen [TESA] immunoblot).
Also, the LQB 123 compound presented greater selective action for the parasite highly infective trypomastigote forms with selectivity index higher than 16 for bloodstream trypomastigotes and higher than 21 for metacyclic trypomastigotes (Table 1).