The etiological agents of HVL are trypanosomatid
protozoans of the genus Leishmania, which are obligate intracellular parasites of cells of the mononuclear phagocytic system and can have two forms: flagellate or promastigote.
Hunter, Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid
The Woo technique was applied to identify trypanosomatid
flagellates from total blood samples in accordance with WOO (1969).
Stewart et al., "Design and synthesis of a series of melamine-based nitroheterocycles with activity against trypanosomatid
parasites," Journal of Medicinal Chemistry, vol.
The difference in kDNA arrangements of trypanosomatid
species is clearly visible under EM .
Analysing all these results, we can conclude that there is a relationship between particular physicochemical features of flavonoids, their trypanosomatid
activities, and TEAC, corroborating previously discussed results.
Trypanosoma cruzi Y strain was provided by the Trypanosomatid
Collection of the Oswaldo Cruz Institute, Fiocruz, Brazil.
protozoa: A simplified DNA isolation procedure.
However, despite its transmission of trypanosomatid
parasites to the plants, it is not clear if the insect is able to reproduce on them or not.
Several natural products have showed to be as selective trypanothione reductase inhibitors in previous studies involving parasites of trypanosomatid
class (Gallo et al., 2008; Campos et al., 2010; Macari et al., 2011).