troponin I


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Related to troponin I: Troponin T

troponin I

Cardiology A contractile protein that ↑ in serum after myocardial necrosis; it is a sensitive and specific marker of acute MI, and better than CK-MB as a cardiac injury marker Indications Acute, recent, or perioperative MI, cardiac contusion, heart allograft rejection, assessment of side-branch occlusion during coronary revascularization procedures or thrombolysis. See Myocardial infarction. Cf Surrogate marker.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

troponin I

A protein that is released into the blood by damaged heart muscle (but not skeletal muscle), and therefore is a highly sensitive and specific indicator of recent myocardial infarction.
See also: troponin
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Cardiac troponin is equally important in the area of risk stratification, where increases clearly hold prognostic significance with contemporary cardiac troponin assays.
In a multivariate analysis, an elevated cardiac troponin I value upon admission was the most powerful predictor of in-hospital mortality, he said.
[4] Nonstandard abbreviations: CK, creatine kinase; RI, reference interval; cTnT, cardiac troponin T; hs-cTnT, high-sensitivity cTnT; cTnI, cardiac troponin I; hs-cTnI, high-sensitivity cTnI; CMR, cardiac magnetic resonance imaging; MADD, multiple acyl-CoA dehydrogenase deficiency.
The Randomized Assessment of Treatment using Panel Assay of Cardiac markers (RATPAC) trial randomly assigned patients to standard assessment including serial troponin testing or point of care testing for CKMB, myoglobin, and troponin I on arrival and at 90 min (37).
The patients with an elevated troponin I level were older, with a mean age of 72 years, compared with a mean age of 66 among the troponin I-negative patients.
To conclude, Point of care cardiac troponin I helps to differentiate between cardiogenic and non-cardiogenic dyspnoea during an emergency especially when other diagnostics are not feasible with decompensating patient.
Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome.
Results: Median value of high sensitivity troponin I was 4.051ng/ml before re-centrifugation and 3.689 ng/ml after recentrifugation.
Armstrong, "Causes of elevated troponin I with a normal coronary angiogram," Internal Medicine Journal, vol.
For patients with suspected AMI, current guidelines recommend analyzing cardiac troponin I at admission and then three hours later, to determine if the level warrants admission or discharge.
(1997) The C terminus of cardiac troponin I is essential for full inhibitory activity and [Ca.sup.2+] sensitivity of rat myofibrils.