tropomyosin


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tropomyosin

 [tro″po-mi´o-sin]
a muscle protein of the I band that inhibits contraction by blocking the interaction of actin and myosin, except when influenced by troponin.

tro·po·my·o·sin

(trō'pō-mī'ō-sin),
A fibrous protein extractable from muscle; sometimes specified as tropomyosin B to distinguish it from tropomyosin A (paramyosin) prominent in mollusks.

tropomyosin

/tro·po·my·o·sin/ (-mi´o-sin) a muscle protein of the I band that inhibits contraction by blocking the interaction of actin and myosin, except when influenced by troponin.

tropomyosin

(trō′pə-mī′ə-sĭn, trŏp′ə-)
n.
A protein that binds to and stabilizes actin filaments in cells. In skeletal and cardiac muscle cells, tropomysin is released after interacting with troponin and calcium, facilitating the binding of actin to myosin that causes muscle contraction.

tropomyosin

[trop′əmī′əsin]
Etymology: Gk, trepein + mys, muscle
a protein component of sarcomere filaments, which, together with troponin, regulates interactions of actin and myosin in muscle contractions.

tro·po·my·o·sin

(trō'pō-mī'ŏ-sin)
A fibrous protein extractable from muscle; sometimes specified as tropomyosin B to distinguish it from tropomyosin A (paramyosin) prominent in mollusks.

tropomyosin

A regulatory protein in striated muscle concerned with the binding sites for the cross bridges on thin filaments in the SARCOMERE. Tropomyosin reversibly prevents bonding, thereby preventing muscles form being in a continuous state of contraction.

tropomyosin

a long protein molecule found in the grooves of muscle ACTIN filaments. It inhibits muscle contraction by blocking the interaction between the filaments and MYOSIN.

tropomyosin

a muscle protein of the I band that inhibits contraction by blocking the interaction of actin and myosin, except when influenced by troponin.
References in periodicals archive ?
Tropomyosin is the major mollusk allergen: reverse transcriptase polymerase chain reaction, expression and IgE reactivity Marine Biotechnology, v.
These include [Alpha]-actinin, tropomyosin, ezrin, and talin (19).
The thirteen titles carry fully descriptive titles; Composition and structure; Muscle cell differentiation and growth; Proteins of thick filament; Proteins of the thin filament - actin, tropomyosin and troponin; Cytoskeletal and other proteins of the myofibrils; Sacroplasmic reticulum; Contraction and rigor mortis; Skeletal muscle growth and protein metabolism; Skeletal muscle fibre types; Cardiac and smooth muscle; Sacroplasmic proteins; The connective tissues - collagen, elastin and ground substance; and Postmortem changes during conversion of muscle to meat.
Structural basis for Ca2+-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin.
We found significant correlations between several factors (including tropomyosin [TPM] 1, TMP2, and TMP3) and gene expression in IMAT and OMAT.
Array BioPharma, a clinical stage publicly traded pharmaceutical company, has collaborated with Asahi Kasei Pharma, a biopharmaceutical company, to develop and commercialise certain Tropomyosin receptor kinase A inhibitors, including Array's ARRY-954, it was reported on Friday.
MiR21-5p is known to function as an oncogene by targeting tumor suppressor genes including tropomyosin 1, programmed cell death 4, and phosphatase and tensin homolog, leading to cell proliferation and inhibition of apoptosis and regulation of cancer invasion and metastasis in breast cancer (20-22).
6) A tropomyosin molecule is thought to be a canonical coiled-coil protein, about 40 nm in length, which binds to actin filament covering seven contiguous actin protomers (monomers), (7) with the length of an actin protomer being about 5.
Tropomyosin receptor kinases (TRKA through TRKC) bind the neurotrophin family of ligands, including nerve growth factor, and have been implicated in tumorigenesis.
Cell motility Actin Actin Actin Actin Actin 1 Beta-actin Tropomyosin Troponin T-1 Beta-tubulin Calponin 7.