trophoblast


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Related to trophoblast: chorion, placenta, cytotrophoblast, blastocyst cavity

trophoblast

 [trof´o-blast]
the peripheral cells of the blastocyst, which attach the zygote (fertilized ovum) to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.

troph·o·blast

(trof'ō-blast, trō'fō-blast),
The mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself but contribute to formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
Synonym(s): chorionic ectoderm
[tropho- + G. blastos, germ]

trophoblast

/tro·pho·blast/ (tro´fo-blast) the peripheral cells of the blastocyst, which attach the blastocyst to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism.trophoblas´tic

trophoblast

(trō′fə-blăst′)
n.
The outermost layer of cells of the mammalian blastocyst that attaches the fertilized ovum to the uterine wall and serves as a nutritive pathway for the embryo.

tro′pho·blas′tic adj.

trophoblast

[trof′əblast′]
Etymology: Gk, trophe + blastos, germ
the outermost layer of tissue that forms the wall of the blastocyst of placental mammals in the early stages of embryonic development. It functions in the implantation of the blastocyst in the uterine wall and in supplying nutrients to the embryo. At implantation the cells differentiate into two layers: the inner cytotrophoblast, which forms the chorion, and the syncytiotrophoblast, which develops into the outer layer of the placenta. Also called trophectoderm. trophoblastic, adj.

troph·o·blast

(trō'fō-blast)
The mesectodermal cell layer covering the blastocyst, which erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself, but contribute to the formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two-layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
[tropho- + G. blastos, germ]

trophoblast

The outer layer of the BLASTOCYST.

trophoblast

the outermost layer of cells surrounding the BLASTOCYST, consisting of embryonic epithelium, which subsequently encloses all the embryonic structures of the developing mammal and forms the outer layer of the CHORION and the embryonic side of the placenta.

Trophoblast

The tissues that surround an embryo and attach it to the uterus.
Mentioned in: Choriocarcinoma

troph·o·blast

(trō'fō-blast)
Mesectodermal cell layer covering the blastocyst that erodes uterine mucosa and through which embryo receives nourishment from mother.
[tropho- + G. blastos, germ]

trophoblast

the peripheral cells of the blastocyst, which attach the fertilized ovum to the uterine wall and contribute to the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.
References in periodicals archive ?
Those special operatives are known as extra-villous trophoblast cells; they infiltrate the uterus and open up maternal blood vessels.
Pre-eclampsia and maternal anaemia display reduced apoptosis and opposite invasive phenotypes of extravillous trophoblast.
Roth and Fisher stated that high concentrations of IL-10 reduces the trophoblast invasion which in turn is a major cause of preeclampsia (16).
b) alterations in trophoblast turnover differ between PE and IUGR.
If the trophoblast is allowed to invade too far into the womb, it can trigger cancer of the placenta in the mother.
The possible reasons (7) could be summarized as: (a) a mild state of immunosuppression in pregnancy, (b) poor allo-antigenic expression of the trophoblast, (c) the trophoblast contains some strong locally acting cytokines and growth factors which suppress the immune response mechanism, (d) the placenta is resistant to attack by the maternal antibody or cell mediated damage due to the presence of a non-specific blocking antibody.
Chapter twenty focuses on ectopic pregnancy and chapter twenty-one diseases of the trophoblast.
It is formed when the chorion, consisting of trophoblast tissue and blood vessel-containing mesoderm, fuses with the uterine wall.
Dr Fiona Lyall, a miscarriage expert at Yorkhill Hospital, has found that, during the normal pregnancy, cells from the placenta, called trophoblast increase the blood supply to the embryo and allow it to grow.
Isolation of Petal Trophoblast Cells from Peripheral Blood of Pregnant Women, 336 LANCET 197 (1990).
The inner cell mass and trophoblast form two distinct cell layers by the sixty-four-cell stage, neither contributing cells to the other.
An in vitro study showed that BDNF and its specific receptor, tyrosine kinase (TRKB), are also involved in embryo implantation, subsequent placental development, and fetal growth by stimulating trophoblast cell growth and survival.