trophoblast


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trophoblast

 [trof´o-blast]
the peripheral cells of the blastocyst, which attach the zygote (fertilized ovum) to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.

troph·o·blast

(trof'ō-blast, trō'fō-blast),
The mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself but contribute to formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
Synonym(s): chorionic ectoderm
[tropho- + G. blastos, germ]

trophoblast

/tro·pho·blast/ (tro´fo-blast) the peripheral cells of the blastocyst, which attach the blastocyst to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism.trophoblas´tic

trophoblast

(trō′fə-blăst′)
n.
The outermost layer of cells of the mammalian blastocyst that attaches the fertilized ovum to the uterine wall and serves as a nutritive pathway for the embryo.

tro′pho·blas′tic adj.

trophoblast

[trof′əblast′]
Etymology: Gk, trophe + blastos, germ
the outermost layer of tissue that forms the wall of the blastocyst of placental mammals in the early stages of embryonic development. It functions in the implantation of the blastocyst in the uterine wall and in supplying nutrients to the embryo. At implantation the cells differentiate into two layers: the inner cytotrophoblast, which forms the chorion, and the syncytiotrophoblast, which develops into the outer layer of the placenta. Also called trophectoderm. trophoblastic, adj.

troph·o·blast

(trō'fō-blast)
The mesectodermal cell layer covering the blastocyst, which erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself, but contribute to the formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two-layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
[tropho- + G. blastos, germ]

trophoblast

The outer layer of the BLASTOCYST.

trophoblast

the outermost layer of cells surrounding the BLASTOCYST, consisting of embryonic epithelium, which subsequently encloses all the embryonic structures of the developing mammal and forms the outer layer of the CHORION and the embryonic side of the placenta.

Trophoblast

The tissues that surround an embryo and attach it to the uterus.
Mentioned in: Choriocarcinoma

troph·o·blast

(trō'fō-blast)
Mesectodermal cell layer covering the blastocyst that erodes uterine mucosa and through which embryo receives nourishment from mother.
[tropho- + G. blastos, germ]

trophoblast

the peripheral cells of the blastocyst, which attach the fertilized ovum to the uterine wall and contribute to the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.
References in periodicals archive ?
Too few or too many trophoblast cells can mean disaster for the fetus and mother.
However, Yoel Sadovsky, MD, who also presented at the meeting, explained that his lab's ex-vivo studies show that primary human trophoblasts have inherent resistance to a number of viruses--and that trophoblasts are refractory to direct infection with the Zika virus.
The human choriocarcinoma-derived trophoblast cell line (Bewo cells) obtained from the Cell Bank of Chinese Academy of Science were cultured in 10% fetal bovine serum-DMEM/F-12 (Thermo Fisher Scientific, USA) supplemented with 100 units/ml penicillin and 100 [micro]g/ml streptomycin (Gibco, USA) at 37[degrees]C in a humidified atmosphere of 95% air and 5% CO[sub]2.
It is not certain why, in PE cases, the trophoblast cannot perform its functions of invasion and remodeling of uterine vessels properly.
Whitley, "Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide," British Journal of Pharmacology, vol.
The relation of increased uterine artery blood flow resistance and impaired trophoblast invasion in pre-eclamptic pregnancies.
Lower PDW as an indicator of platelet activation in CM may suggest that CM requires less PLT activation than healthy pregnancy that needs stronger trophoblast invasion for normal placental development.
In contrast, P57KIP2 expression in villous cytotrophoblast, villous stromal cells and ex-travillous trophoblast was absent or markedly decre-ased in 17 (34%) complete hydatidiform mole (Fig.
It has been proposed that a breach in the trophoblast layer lining the chorionic villi may result in contact of Hofbauer cells (specialised fetal macrophages) with maternal blood and amniotic fluid.
Several processes regulated by estrogens, such as uteroplacental blood flow, trophoblast invasion, and syncytialization are necessary for healthy pregnancy (Albrecht and Pepe 1999; Cronier et al.