troleandomycin


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troleandomycin

 [tro″le-an-do-mi´sin]
a macrolide antibiotic used in treatment of pneumonia and streptococcal infections.

troleandomycin

/tro·le·an·do·my·cin/ (tro″le-an-do-mi´sin) a macrolide antibiotic used in the treatment of pneumococcal pneumonia and Group A infections.

troleandomycin

[trol′ē·an′dōmī′sin]
a macrolide antibiotic.
indications It is prescribed in the treatment of certain infections, including pneumococcal pneumonia and group A streptococcal infections of the upper respiratory tract. It has orphan drug status for the treatment of corticosteroid-dependent asthma due to its steroid-sparing properties.
contraindications Known hypersensitivity to this drug or concomitant use of ergot alkaloids prohibits its use.
adverse effects Among the more serious adverse effects are GI disturbances, mild to severe allergic reactions (including anaphylaxis), and hepatotoxicity.

troleandomycin

the triacetyl ester of oleandomycin; a macrolide antibiotic, similar to erythromycin. Called also triacetyloleandomycin.
References in periodicals archive ?
A related macrolide antibiotic, troleandomycin, has been shown to increase quinine exposure in a pharmacokinetic study .
John's Wort Primidone Sulfinpyrazone Weak/moderate Nefazodone Quinidine inhibitors Nevirapine Ranitidine Norfloxacin Sertindole Norfluoxetine Troleandomycin Omeprazole Verapamil Paroxetine Zafirlukast Propoxyphene Zileuton Strong inhibitors * Ketoconazole Ritonavir Nelfinavir Saquinavir * Requires dosage modification when used in combination with PDE5 inhibitor.
It should not be used within at least 72 hours of treatment with ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, and nelfinavir.
Contraindicated in patients with hepatic dysfunction, and in those who are taking mibefradil, erythromycin, clarithromycin, troleandomycin, quinine, ketoconazole, or itraconazole.
Other macrolide antibiotics include dirithromycin and troleandomycin, which are not used extensively in children, and tacrolimus, which is used in solid organ transplantation as an immunosuppressant.
Of particular interest for dangerous interactions are enoxacin, fluvoxamine, mexiletine, propanolol, and troleandomycin.
17) The CYP3A inhibitors included in the analysis were nitroimidazole antifungal agents, diltiazem, verapamil, and troleandomycin.
Drug Reference Erythromycin and troleandomycin [112] Cyclosporine [113] FK506 [114] Lidocaine [115] Nifedipine [116] Tamoxifen [117] Others [118]
itraconazole, miconazole, troleandomycin, erythromycin,
Inhibition of theophylline clearance by troleandomycin.