triptorelin


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triptorelin

 [trip″to-rel´in]
a synthetic analogue of gonadorelin that on prolonged administration suppresses gonadotropin release; used as triptorelin pamoate as an antineoplastic in the palliative treatment of prostatic carcinoma, administered intramuscularly.

triptorelin

/trip·to·rel·in/ (trip″to-rel´in) a synthetic gonadorelin analogue that on prolonged administration suppresses gonadotropin release; used as t. pamoate as an antineoplastic in the treatment of prostatic carcinoma.

triptorelin

a gonadotropin-releasing hormone used to treat advanced prostate cancer.

triptorelin

Therapeutics A long-acting gonadotropin-releasing hormone analogue, that induces intense reversible hypogonadism by inhibiting LH and, to a lesser degree, FSH release, resulting in ↓ testosterone Indications Advanced prostate and ovarian CA; it may have a role in Rx-refractory sexual deviancy. See Paraphilia.

triptorelin

A synthetic gonadotrophin-releasing hormone used to treat advances cancer of the PROSTATE GLAND. A brand name is Decapeptyl SR.
References in periodicals archive ?
The '438 patent describes administration of a therapeutically effective amount of a CYP17 inhibitor, such as abiraterone acetate, with a therapeutically effective amount of at least one additional therapeutic agent including, but not limited to, an anti-cancer agent, such as mitoxantrone, paclitaxel, docetaxel, leuprolide, goserelin, triptorelin, seocalcitol, bicalutamide, or flutamide, or a steroid, such as hydrocortisone, prednisone, or dexamethasone, the ruling states.
Spherotide's active substance is triptorelin and it is based on encapsulation of the active ingredient in biodegradable microspheres that degrade in the body following injection and create a long-acting effect.
Conventional LHRH agonists currently available on the market include leuprolide acetate, buserelin, goserelin, and triptorelin, each available in depot formulations requiring monthly, three-monthly, four-monthly, or longer-duration injections.
Very few studies have been published on the efficacy of CPA or other androgen-depleting medications like medroxyprogesterone acetate (MPA) or the GnRH analogues [also known as GnRH agonists or luteinising hormone-releasing hormone (LHRH) agonists] like leuprolide, triptorelin and goserelin in the treatment of hypersexuality and sexually inappropriate behaviour, and high-quality evidence in favour of their use is lacking.
Izmedu nekoliko agonista gonadotropnog otpustajuceg hormona najcesce se koriste buserelin 0,5 mg, triptorelin 0,2 mg i leuprolid (0,5-4 mg).
When he was seven years old he developed signs of precocious puberty and was treated with triptorelin 3.
1 mg triptorelin (Diphereline, Ipsen Pharma Biotech, France), started on day 21 of the previous menstrual cycle and continued until the administration of human chorionic gonadotropin (hCG).
GnRH agonists, such as buserelin and triptorelin, have been used to induce remission of symptoms by causing ovarian suppression.
Triptorelin is an agonist analogue of the natural gonadotropin-releasing hormone (GnRH).
Ovarian suppression with triptorelin during chemotherapy for early-stage breast cancer significantly increased the chances that women would recover their long-term ovarian function, according to a multicenter phase III open-label study published in JAMA.
05 mg GnRH agonist Triptorelin (Ferring, Wittland, Germany) starting on day 20 of the previous cycle, followed by recombinant gonadotrophin stimulation with either injection of Puregon (Organon, Oss, The Netherlands) or injection of Gonal F (Merck Serono, Geneva, Switzerland).