triptan


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triptan

(trĭp'tan),
A colloquial short form for those migraine drugs that have triptan in their names.

triptan

(trĭp′tn)
n.
Any of a class of drugs that act as agonists of serotonin, result in cranial vasoconstriction, and are used for the prophylaxis and treatment of migraine headaches.

triptan

A class of medications used to treat cluster and migraine headaches. Members of this class act as agonists at 5-hydroxytryptamine (5-HT) receptors in the brain. Each of them has a generic name that ends in “-triptan, ” including frovatriptan, naratriptan, rizatriptan, and sumatriptan.
References in periodicals archive ?
The cardiovascular safety profile of triptans was thoroughly investigated by the Triptan Cardiovascular Safety Expert Panel.
It is longer-acting than other triptans, with a half-life of 26 hours.
Neither treatment offers efficacy superior to that of the triptans, but both offer alternatives for triptan nonresponders.
Seven triptans are currently approved for adult migraine treatment, but none of them are approved for use in adolescents, noted Dr.
Triptans tend to be less effective the longer a patient waits.
Lasmiditan does not interact with vasoconstrictor 5-HT1B receptors activated by triptans.
In a randomised study of 1,380 people with moderate or severe migraine telcagepant was as effective as zolmitriptan, the most commonly used triptan, and was associated with fewer adverse effects, Dr Tony Ho of Merck Research Laboratories in Philadelphia said in the report.
In these patients, combining hormone manipulation with triptan treatment may help.
Emerging evidence suggests combining a triptan plus an NSAID may produce higher response rates and more durable responses.
4 billion migraine market in 2010 was triptan drugs, prescribed for the acute treatment of migraine.
concerning" the authors noted, was the fact that 21% of older migraine patients with cardiac contraindications at the time of the study had received a triptan prescription.