The cardiovascular safety profile of triptans
was thoroughly investigated by the Triptan
Cardiovascular Safety Expert Panel.
It is longer-acting than other triptans
, with a half-life of 26 hours.
Neither treatment offers efficacy superior to that of the triptans
, but both offer alternatives for triptan
Ask patients who discontinue triptan
therapy why they made that decision.
are currently approved for adult migraine treatment, but none of them are approved for use in adolescents, noted Dr.
tend to be less effective the longer a patient waits.
Lasmiditan does not interact with vasoconstrictor 5-HT1B receptors activated by triptans
In a randomised study of 1,380 people with moderate or severe migraine telcagepant was as effective as zolmitriptan, the most commonly used triptan
, and was associated with fewer adverse effects, Dr Tony Ho of Merck Research Laboratories in Philadelphia said in the report.
In these patients, combining hormone manipulation with triptan
treatment may help.
Emerging evidence suggests combining a triptan
plus an NSAID may produce higher response rates and more durable responses.
4 billion migraine market in 2010 was triptan
drugs, prescribed for the acute treatment of migraine.
concerning" the authors noted, was the fact that 21% of older migraine patients with cardiac contraindications at the time of the study had received a triptan