The older drugs (called first-generation antihistamines), which include chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), hydroxyzine (Hyzine) and triprolidine
(Zymine), cause drowsiness and increase the risk of vehicle and occupational injuries.
Examples of common ingredients in cough and cold medications, by class of medication Class Examples Antihistamine Acrivastine, brompheniramine, carbinoxamine, (first generation) chlorpheniramine, cyproheptadine, diphenhydramine, doxylamine, triprolidine
Antipyretic Acetaminophen, ibuprofen and analgesic Cough suppressant Benzonatate, codeine, dextromethorphan, (antitussive) hydrocodone Expectorant Guaifenesin Nasal decongestant Ephedrine, phenylephrine, phenylpropanolamine, pseudoephedrine
Loratadine is among the first of a new generation of antihistamines that is designed to be less sedating at recommended dos ages than such antihistamines as diphenhydraminc HCL (used in Benadryl) or triprolidine
SOME remedies include triprolidine
, diphenhydramine or promethazine, which help unblock your nose and stop you sneezing, although not all scientists agree on whether they work.
The first-generation, or "classic," antihistamines are chlorpheniramine, diphenhydramine, hydroxyzine, and triprolidine
. These drugs are lipophilic and thus cross the blood-brain barrier and attach to [H.sub.1] receptors on brain cells.
NEW YORK--From the 1982 approval of triprolidine
hydrochloride (the antihistamine used in Actifed capsules and syrup) for over-the-counter sale; to the 1995 clearance of ranitidine in the acid reducer Zantac 75, to scores of ingredients found in a multitude of other products, the movement of medications from prescription to O-T-C status has had a major impact on the health care system in the United States.
A double-blind crossover trial of pseudoephedrine and triprolidine
, alone and in combination, for the treatment of allergenic rhinitis.
Ingredients include brompheniramine, chlorpheniramine and triprolidine
. These work in relieving symptoms just as well as prescription medicines do, but they tend to have more side effects than prescription medicines.
Diclofenac sodium (NSAID), diphenhydramine, paracetamol caffeine, paracetamol plus triprolidine
(irrational combinations) have all been used by a large number of patients as selfmedications.
The medicine Sedofan was suspended from the UAE market for containing low dosage of the ingredient Triprolidine