triple therapy

AIDS Any 3-agent antiretroviral regimen—in developing nations, D4T, 3TC and nevirapine—to manage HIV-1 infection; in general, the use of multiple agents of different classes is thought to improve the probability of a positive outcome
Cardiology
(1) The use of 3 agents—e.g., ARBs, beta blockers and ACE inhibitors—to decrease morbidity and mortality in patients with congestive heart failure
(2) Triple antithrombotic therapy The simultaneous use of aspirin, clopidogrel and warfarin. No clots, copious bleeding
Fringe medicine A combination of herbs, yoga, meditation and diet to manage HIV-1+ patients
Gastroenterology A therapy that requires 3 modalities or agents—e.g., TT for H pylori infection includes a proton-pump inhibitor (e.g., omeprazole) and 2 antibiotics (e.g., amoxicillin, clarithromycin)
Hepatology A combination of Zadaxin®, pegylated IFN alpha and ribavirin, used to manage HPV C in nonresponders to IFN and ribavirin alone
Obstetrics The administration of low-dose aspirin, heparin, and prednisone in a habitual aborter with primary antiphospholipid syndrome at an increased risk of DVTs Note: Corticosteroids are ineffective in APS and increase maternal morbidity and foetal prematurity
Oncology—lung The use of 3 different chemotherapeutics—e.g., vinorelbine, gemcitabine, and carboplatin—in patients with non-small cell CA of lung
Oncology—lymphoma Alternating triple therapy The alternating of 3 different chemotherapy regimens—e.g., CHOP-MINE-ESHAP in lymphoma
Oncology—pancreas The use of 3 chemotherapeutics—e.g., gemcitabine, cisplatin, infused fluorouracil—in pancreatic cancer
Pulmonary medicine The use of 3 agents—inhaled corticosteroids, long-acting 2-agonists (e.g., salmeterol) and leukotriene modifiers (e.g., montelukast). Leukotrienes do not help in asthma
Transplantation A 3-agent immunosuppressant regimen—e.g., cyclosporine, azathioprine (or everolimus), and methylprednisolone—to minimize rejection in patients receiving lungs or other transplanted organs See Asthma
Urology The use of hormonal therapy, brachytherapy, and external beam radiation for local control in high-risk prostates See Prostate CA

triple therapy

Infectious disease The use of 3 antibiotics–ampicillin, gentamicin, metronidazole-to 'cover' for acute diverticulitis. See Acute diverticulitis Medtalk A therapy that requires 3 modalities/agents–eg, TT for H pylori includes a proton-pump inhibitor–eg, omeprazole and 2 antibiotics–eg, amoxicillin, clarithromycin.
References in periodicals archive ?
If this latest submission is approved, the labeled indication for Trelegy Ellipta would include a wider population of patients with COPD who are at risk of an exacerbation and require triple therapy.
Trelegy Ellipta is the first once-daily single inhaler triple therapy to be approved in Europe.
The European Medicines Agency (EMA) has granted pharmaceutical firm GlaxoSmithKline (LON: GSK) and Innovia marketing authorisation for their single inhaler triple therapy Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol), Pharma File reported on Thursday.
There's also the Acne Triple Therapy that purifies, resurfaces and heals even the most complex acne condition.
Of patients with genotype 3, 123 received dual therapy and 57 were given triple therapy.
Three clinical trials have shown that the effectiveness of the triple therapy is equal or almost equal to that of combination methotrexate and an antiTNF agent.
The results of analysis of response to triple therapy in RUT positive NUD patients has been shown in Figure 4.
The European Helicobacter Study Group has advised to employ a metronidazole-based triple therapy as choice in treating H.
pylori with PPI-based triple therapy have declined parallel to antibiotic resistance and have been reported to be approximately 75% in the United States and lower than 50% in some areas of Europe (5,6).
Efficacy of amoxycillin and clarithromycin-based triple therapy for Helicobacter pylori eradication: a 10-year trend in Turin, Italy.
Since there was a close temporal relationship between the BCG instillation and the development of symptoms and no other cause was identified, a systemic BCG disease with pneumonitis was assumed and 6-month triple therapy was initiated.
0%, dual therapy including metformin is advised, with triple therapy starting after 1 month if the patient is still not at goal.