triple repeat disorders

triple repeat disorders

a group of hereditary disorders in which a gene mutation on a specific chromosome produces an abnormal form of protein terminated by a long chain of amino acid glutamate repeats; includes Huntington disease, Kennedy disease, Machado-Joseph disease, myotonic dystrophy, fragile X syndrome, and some spinal cerebellar disorders.

tri·ple re·peat dis·or·ders

(trip'ĕl rĕ-pēt' dis-ōr'dĕrz)
A group of hereditary disorders in which a gene mutation on a specific chromosome produces an abnormal form of protein terminated by a long chain of amino acid glutamate repeats; includes Huntington disease, Kennedy disease, Machado-Joseph disease, myotonic dystrophy, fragile X syndrome, and some spinal cerebellar disorders.