tripeptidyl aminopeptidase

tripeptidyl aminopeptidase

(1) Tripeptidyl-peptidase I, EC 3.4.14.9. 
(2) Tripeptidyl-peptidase II, EC 3.4.14.10.
References in periodicals archive ?
The gut showed highest activities of alanyl aminopeptidase, dipeptidyl aminopeptidase (DAP) I, II and IV, and cathepsin B, L and H while head showed highest activities of arginyl, leucyl and tripeptidyl aminopeptidase.
DAP I by 429%, DAP II by 355% and DAP IV by 178%, followed by cathepsin L (246%), cathepsin D (123%), tripeptidyl aminopeptidase (109%), arginyl aminopeptidase (78%), alanyl aminopeptidase (72%), leucyl aminopeptidase (49%), cathepsin H (37%) and proline endopeptidase (19%).
On the other hand, head contained the highest activities of arginyl aminopeptidase (58 nmol/h/mg protein), leucyl aminopeptidase (49 nmol/h/mg protein), tripeptidyl aminopeptidase (51 nmol/h/mg protein) and proline endopeptidase (111 nmol/h/mg protein) than all the remaining body compartments.
Thus alanyl aminopeptidase, arginyl aminopepetidase, leucyl aminopepetidase, dipepetidyl aminopeptidase IV, tripeptidyl aminopeptidase and proline endopeptidase were increased by 72%, 78%, 49%, 178%, 109% and 19%, respectively.
Thus the head contained highest concentrations of arginyl aminopeptidase, leucyl aminopeptidase, tripeptidyl aminopeptidase, proline endopeptidase, and cathepsin D, while the gut contained highest levels of all lysosomal proteases tested in this study (except cathepsin D, which was highest in the thorax part) as well as alanyl aminopeptidase and dipeptidyl aminopeptidase IV out of cytoplasmic proteases.
Thus alanyl aminopeptidase was increased by 53%, arginyl aminopeptidase by 73%, leucyl aminopeptidase by 16%, dipeptidyl aminopeptidase IV by 17%, tripeptidyl aminopeptidase by 148% and proline endopeptidase by 111%.
Thus tripeptidyl aminopeptidase, proline endopeptidase and soluble proteins were increased by 58%, 61% and 24%, respectively while activities of arginyl aminopeptidase and leucyl aminopeptidase were decreased by 37% and 72%, respectively.
Thus arginyl aminopeptidase, leucyl aminopeptidase, dipeptidyl aminopeptidase I, dipeptidyl aminopeptidase II, cathepsin L, cathepsin H and cathepsin D manifested depleted activities while tripeptidyl aminopeptidase and proline endopeptidase activities were raised in surviving treated flies.
In dead flies these proteases manifested mixed response by showing further decreasing trend (such as arginyl and leucyl aminopeptidases and cathepsin L), increasing trend (such as soluble proteins) or adopted the rout of adjustment before death (such as tripeptidyl aminopeptidase, proline endopeptidase, dipeptidyl aminopeptidase I and 11, cathepsin B, H and D).