tripe palm

tripe palm

Velvety thickening of the skin of the palms, giving the skin surface the appearance of the villous lining of the intestines. It is a condition usually found in patients with acanthosis nigricans and some internal organ or external (skin) cancers.
Synonym: acanthosis palmaris
References in periodicals archive ?
By examining the hair, skin, and nails, we are able to diagnose internal organ diseases such as liver failure (jaundice, veins on stomach), thyroid disease (madarosis), sarcoidosis, and infectious diseases (cutaneous manifestations of HIV), diabetes (acanthosis nigricans, tripe palm), polycystic ovary syndrome (acne, hirsutism), and porphyria, just to name a few.
Tripe palm or palmar acanthosis nigricans is a condition in which there is a velvety, rugose thickening of palm, occasionally soles with an enhanced dermatoglyphic pattern resembling 'tripe' (the villous lining of ruminant stomach).1 It is associated with neoplasia in about 90% of cases; it may be the only paraneoplastic manifestation in 30-40% of cases.2 It may coexist with malignant acanthosis nigricans or sign of Leser-Trelat.2
* Tripe Palms. This very rare paraneoplasia has been reported in fewer than 100 patients in the literature, and most have underlying gastrointestinal or pulmonary malignancies.