triorganotin

triorganotin

A family of highly toxic organotins which, depending on the substituted organic group, have been deployed as acaricides, bactericides, fungicides and miticides.
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The application of the vast array of excellent synthetic procedures using triorganotin hydrides to pharmaceutical synthesis is precluded by the toxicity of organ tin.
Plus, the industry is also faced with the implementation of regulations eliminating the use of triorganotin compounds that are used to prevent the fouling of ships hulls by barnacles, seaweed, and bacteria.
The production worldwide of organotin compounds was some 35 000 tons in 1980 of which 8 000 tons were triorganotin compounds for biocidal use; 3 000 tons were produced for antifouling paints, 1 000 tons for wood preservatives, 3 000 tons for agrochemicals and 1 000 tons for disinfectants.
Toxicity of triorganotin compounds: comparative in vivo studies with a series of trialkyltin compounds and triphenyltin chloride in male rats.