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a folic acid antagonist structurally related to methotrexate, used as the glucuronate salt, in combination with leucovorin, to treat Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome, administered intravenously.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
trimetrexateAn inhibitor of the enzyme DIHYDROFOLATE REDUCTASE. It is used to treat Pneumocystis carinii pneumonia in people with AIDS. A brand name is Neutrexin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005