trimethyllysine

trimethyllysine

component of histone proteins; precursor of carnitine, the coenzyme of fatty acid oxidation.
References in periodicals archive ?
Carnitine biosynthesis: b-Hydroxylation of trimethyllysine by an a-ketoglutarate-dependent mitochondrial dioxygenase.
The rate-limiting step in the pathway is the hepatic enzyme, [gamma]-butyrobetaine hydroxylase; however, the rate of carnitine biosynthesis is mainly determined by the rate of protein turnover that supplies trimethyllysine (19).
G]-dimethyl-arginine, N-epsilon-mono-, di-, and trimethyllysine, and glucosylgalactosyl- and galactosyl-delta-hydroxylysine from human urine.
Carnitine synthesis in mammals is carried out from the turnover of proteins containing lysine residues which are previously posttranslationally trimethylated with release of trimethyllysine (7-18).
beta]-Hydroxylation of trimethyllysine by an [alpha]-ketoglutarate-dependent mitochondrial dioxygenase.
Isolation and identification of N-G,N-G and N-G,N'-G-dimethyl-arginine, N-[member of]-mono-, di-, and trimethyllysine, and glucosylgalactosyl--and galactosyl-[delta]-hydroxylysine from human urine.
Determination of free trimethyllysine in plasma and tissue specimens by high-performance liquid chromatography.
Labeled trimethyllysine load depletes unlabeled carnitine in premature infants without evidence of incorporation.
Isolation and identification of N-G,N-G-and N-G,N'-G-dimethyl-arginine, N-epsilon-mono, di-, and trimethyllysine, and glucosylgalactosyl- and gal actosyl-hydroxylysine from human urine.