trimethadione


Also found in: Dictionary, Encyclopedia, Wikipedia.

trimethadione

 [tri″meth-ah-di´ōn]
an anticonvulsant with analgesic properties, administered orally for treatment of petit mal epilepsy.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

trimethadione

(trī-mĕth′ə-dī′ōn′)
n.
A white crystalline substance, C6H9NO3, used as an anticonvulsant in the treatment of epilepsy.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

trimethadione

Tridione® Pharmacology An oxazolidinedione  used for absence seizures Adverse effects Sedation, blurring of vision, exfoliative dermatitis, rashes, hepatitis, nephrosis, death
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
An example is CYP2E1 function, in which in vitro liver bank studies (Figure 4A, B) generally agree with in vivo drug metabolism data for the CYP2E1 substrate trimethadione (Figure 5) (Nakamura et al.
Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1.
Trimethadione is the only dione available in the United States; paramethadione is used overseas and in Canada for absence seizures.
Medications Known to Aggravate Myasthenia Gravis "Mycin" antibiotics Clindamycin Vancomycin Polymyxin B Amikacin Kanamycin Neomycin Streptomycin Tobramycin Morphine Diuretics Procainamide Beta-Blockers Atenolol Nadolol Propranolol Timolol Succinylcholine Over-the-counter cold medications (many contain quinine Curare Quinidine D Penicillamine Chloroquine Trimethadione
Specific drugs, such as ethosuximide and trimethadione which may act by blocking T-type voltage dependent [Ca.sup.++] channels, are also effective in the PTZ test.