In a study on 3[beta]-HSD enzyme activity of the porcine corpus luteum, in vitro treatment of cultured luteal cells with T3 showed a marked increase in progesterone concentrations, measured via radioimmunoassay, against trilostane
, a competitive inhibitor 3[beta]-HSD.
Among the 20 dogs with HAC, 19 dogs were treated with trilostane
Mitotane, Ketoconazole and Trilostane
are three treatments commonly used in management of PDH in dogs (Boari and Aste, 2003).
Inhibition of progesterone secretion with trilostane
for mid-trimester termination of pregnancy: randomized controlled trials.
Adrenal necrosis in a dog receiving trilostane
for the treatment of hyperadrenocorticism.
My vet and I have decided to treat her with trilostane
and see how she does.
The agents inhibiting steroidogenesis include: metyrapone, ketoconazole, mitotane, aminoglutethimide, trilostane
The Food and Drug Administration now states that Vetoryl is the only FDA-approved animal drug containing trilostane
as the active ingredient.
OVX/ADX rats treated with 17-beta-estradiol benzoate (EB) were given trilostane
, aminoglutethimide, RU486, or aCSF and tested 48 h after EB treatment for reproductive behaviors.
The West Midlands pet drug supplier and manufacturer has been granted the sole US intellectual property rights to the chemical compound Trilostane
Food and Drug Administration (FDA) announced the approval of the drug trilostane
(Vetoryl) for the treatment of hyperadrenocorticism (Cushing's disease) in dogs.