trilostane


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trilostane

A drug that interferes with the natural synthesis of steroids and is used to treat breast cancer in post-menopausal women. A brand name is Modrenal.

trilostane

an inhibitor of adrenal, ovarian and placental steroids. Used in the treatment of hyperadrenocorticism.
References in periodicals archive ?
In a study on 3[beta]-HSD enzyme activity of the porcine corpus luteum, in vitro treatment of cultured luteal cells with T3 showed a marked increase in progesterone concentrations, measured via radioimmunoassay, against trilostane, a competitive inhibitor 3[beta]-HSD.
Mitotane, Ketoconazole and Trilostane are three treatments commonly used in management of PDH in dogs (Boari and Aste, 2003).
Inhibition of progesterone secretion with trilostane for mid-trimester termination of pregnancy: randomized controlled trials.
Adrenal necrosis in a dog receiving trilostane for the treatment of hyperadrenocorticism.
My vet and I have decided to treat her with trilostane and see how she does.
The agents inhibiting steroidogenesis include: metyrapone, ketoconazole, mitotane, aminoglutethimide, trilostane, etomidate.
The Food and Drug Administration now states that Vetoryl is the only FDA-approved animal drug containing trilostane as the active ingredient.
OVX/ADX rats treated with 17-beta-estradiol benzoate (EB) were given trilostane, aminoglutethimide, RU486, or aCSF and tested 48 h after EB treatment for reproductive behaviors.
The West Midlands pet drug supplier and manufacturer has been granted the sole US intellectual property rights to the chemical compound Trilostane.
Food and Drug Administration (FDA) announced the approval of the drug trilostane (Vetoryl) for the treatment of hyperadrenocorticism (Cushing's disease) in dogs.
OTCBB:BIOV) today announced that it has closed a transaction with Dechra Pharmaceuticals, PLC in which Dechra will sublicense Bioenvision's marketing and development rights to trilostane for animal health applications within the United States and Canada.