triglyceride


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triglyceride

 [tri-glis´er-īd]
a compound consisting of three molecules of fatty acids bound with one molecule of glycerol; a neutral fat that is the usual storage form of lipids in animals.



Elevated serum triglycerides are now considered as important as high cholesterol levels in the development of ischemic heart disease. The normal range for serum triglycerides is 0 to 160 mg/100 ml.

tri·ac·yl·glyc·er·ol

(trī-as'il-glis'ĕr-ol),
Glycerol esterified at each of its three hydroxyl groups by a fatty (aliphatic) acid; for example, tristearoylglycerol.
Synonym(s): triglyceride

triglyceride

(trī-glĭs′ə-rīd′)
n.
A naturally occurring ester of three fatty acids and glycerol that is the chief constituent of fats and oils.

triglyceride  

Triacylglycerol A long chain fatty acid ester of glycerol; TGs constitute 95% of fat by weight, and are the major form of stored lipids ↑ in Acute MI, alcoholic cirrhosis, untreated DM, high carbohydrate diet, certain forms of hyperlipoproteinemia, HTN, hypothyroidism, nephrotic syndrome, pregnancy, OCs, estrogens ↓ in Congenital β-lipoproteinemia, hyperthyroidism, malnutrition, vigorous exercise, therapy with ascorbic acid, clofibrate, metformin, phenformin. See Medium chain triglyceride. Cf Cholesterol.

tri·ac·yl·glyc·er·ol

(trī-as'il-glis'ĕr-ol)
Glycerol esterified at each of its three hydroxyl groups by a fatty (aliphatic) acid.
Synonym(s): triglyceride.

triglyceride

see FAT.

Triglyceride

A substance formed in the body from fat in the diet. Triglycerides are the main fatty materials in the blood. Together with protein, they make up high- and low-density lipoproteins (HDLs and LDLs). Triglyceride levels are important in the diagnosis and treatment of many diseases including high blood pressure, diabetes, and heart disease.

Patient discussion about triglyceride

Q. Improving High Triglycerides I take Tricor for high triglyceride levels; I have a healthy level of total cholesterol, with low LDL, very good HDL. I am now being treated for hypothyroidism, but my doctor says that it's also genetic (I had almost the exact same level number as my brother). How can I work to get my triglycerides under control?

A. High level of triglycerides are generally both genetic and diet related. If you are consuming a high fat containing diet then your level of triglycerides will be increased. On the other hand, regardless of your good cholesterol levels, if you start lowering the amount of fat in your food (less oil, less sweets, less red meat) and combine it with physical activity you can lower your triglycerides level, especially if you are already on medications.

More discussions about triglyceride
References in periodicals archive ?
Luckily, unlike the case of LDL "bad" cholesterol, "triglycerides are much more sensitive to lifestyle changes, with reductions in carbohydrates, weight, alcohol and increases in physical activity associated with reductions [of triglyceride levels] by almost 50%," Hirsh noted.
Contrary to common perception, the formula that contains both EPA and DHA does not increase the "bad" form of cholesterol (LDL-C) among most people with high triglyceride levels (200-499 mg/dL).
"We are increasingly recognizing that elevated triglycerides represent a major issue and should not be ignored," says Steven Nissen, MD, chairman of Cardiovascular Medicine at Cleveland Clinic."
The median baseline level of triglycerides among the subjects was 216 milligrams per decilitre well above the cut-off for what is considered a normal level, which is 150 milligrams per decilitre.
When it comes to determining health risks, cholesterol numbers are given a great deal of attention, but there's another substance that's often neglected: triglycerides.
Previous Kowa research has shown that this first in class selective PPAR-a modulator is more potent than currently available therapies in lowering triglycerides, ApoC3, and remnant cholesterol and increasing high-density-lipoprotein cholesterol.
Low Serum triglyceride levels as predictors of cardiac death in heart failure patients.
* To correlate postprandial triglyceride levels and carotid intima media thickness.
One in 20 Amish people has a mutation that destroys a gene, APOC3, involved in triglyceride metabolism, as compared with one in 150 Americans generally.
Results also showed increased benefits after 8 weeks of treatment, with patients on a daily dose of 4 grams of CaPre, registering a mean triglyceride decrease of 21.6% and an absolute mean improvement of 14.3% as compared to Standard of Care, in which, due to lipid lowering medication adjustment, a significant improvement in triglyceride levels was observed during the trial between 4 weeks and 8 weeks.
While management of hyperlipidemia usually focuses on total and LDL cholesterol levels, very high triglyceride levels pose a risk for pancreatitis, and moderately high levels may confer cardiovascular risk.