trifluridine


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trifluridine

 [tri-floor´ĭ-dēn]
an antiviral compound that interferes with viral DNA synthesis, used topically in the treatment of keratitis and keratoconjunctivitis caused by human herpesviruses 1 and 2.

trifluridine

/tri·flur·i·dine/ (-floor´ĭ-dēn) an antiviral compound that interferes with viral DNA synthesis, used topically in the treatment of keratitis and keratoconjunctivitis caused by human herpesviruses 1 and 2.

trifluridine (ophthalmic) (trī´floor´-idēn´ ofthal´mik),

n brand name: Viroptic ophthalmic solution;
drug class: antiviral;
action: inhibits viral deoxyribonucleic acid (DNA) synthesis and replication;
uses: treatment of primary keratoconjunctivitis, recurring epithelial keratitis, and keratitis associated with herpes simplex virus types 1 and 2.

trifluridine

an antiviral agent used topically in the treatment of herpesvirus infections of the eye.
References in periodicals archive ?
Japan), today announced the New Drug Application (NDA) for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), has been accepted for review by the U.
Food and Drug Administration (FDA) for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride).
Food and Drug Administration (FDA) granted Fast Track designation for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an oral combination anticancer drug under investigation for the treatment of refractory metastatic colorectal cancer (mCRC), and that the Company has initiated a rolling NDA submission to the FDA.
Whitten represents the initial step in the transition of the company to a more fully integrated clinical development and commercial entity as it prepares for the potential marketing approval of its lead compound, TAS-102, an oral combination anticancer drug (nonproprietary names: trifluridine and tipiracil hydrochloride).
Tokyo, President: Masayuki Kobayashi) announced on March 24 that it has obtained approval in Japan from the Ministry of Health, Labour and Welfare to manufacture and market the oral combination anticancer drug "Lonsurf(R) combination tablet T15, T20" (nonproprietary names: trifluridine and tipiracil hydrochloride; development code: TAS-102), for the treatment of patients with unresectable advanced or recurrent colorectal cancer (only if refractory to standard therapies).
Falcon Unveils Trifluridine Ophthalmic Solution, 1% 97
King directed many drug projects, resulting in numerous approvals, including zidovudine (Retrovir(R), AZT), acyclovir (Zovirax(R)) and trifluridine (Viroptic(R)), among others.
Among the Burroughs Wellcome products contained in the "Disaster Relief" packets are: Zovirax(R) brand acyclovir, Retrovir(R) brand zidovudine, Lanoxin(R) brand digoxin, Wellbutrin(R) brand bupropion, Septra(R) brand trimethoprim/sulfamethoxazole, Imuran(R) brand azathioprine, Leukeran(R) brand chlorambucil, Purinethol(R) brand mercaptopurine, Cortisporin(R) Opthalmic (polymyxin B-sulfate), Cortisporin Otic (polymyxin B-neomycin hydrocortisone), Neosporin(R) (polymyxin B-sulfate bacitracin zinc-neomycin sulfate), Polysporin(R) (polymyxin B-bacitracin), PediOtic(R) (polymyxin B-sulfate neomycin sulfate-hydrocortisone), Viroptic(R) brand trifluridine, Zyloprim(R) brand allopurinol and Nix(R) Creme Rinse 1 percent permethrin.
Food and Drug Administration today approved Lonsurf (a pill that combines two drugs, trifluridine and tipiracil) for patients with an advanced form of colorectal cancer who are no longer responding to other therapies.
announced that it has submitted a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an oral combination anticancer drug intended for use in the treatment of refractory metastatic colorectal cancer (mCRC).
Topical trifluridine, iododeoxyuridine or vidarabine are used for treatment (2,50,59).
After examination, the ophthalmologist stated this was not a bacterial infection but a viral infection, and prescribed trifluridine, an antiviral drug for topical treatment of epithelial keratitis caused by herpes simplex virus.