trifluoperazine


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Related to trifluoperazine: Trifluoperazine hydrochloride

trifluoperazine

 [tri″floo-o-per´ah-zēn]
a phenothiazine derivative used in the form of the hydrochloride salt as an antipsychotic agent.

trifluoperazine

/tri·flu·o·per·a·zine/ (tri-floo-o-per´ah-zēn) a phenothiazine derivative used as the hydrochloride salt as an antipsychotic.

trifluoperazine

Stelazine®, Etalazine® Psychiatry An oral antipsychotic and anxiolytic phenothiazine analogue Adverse effects Extrapyramidal effects, sedation, hypotension

trifluoperazine

An antipsychotic drug used mainly to treat SCHIZOPHRENIA. A brand name is Stelazine. The drug is also formulated with TRANYLCYPROMINE under the brand name Parstelin.
References in periodicals archive ?
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.
Through experiments in human cells, human lung cancer tissue and mouse lung tissue, the team found that trifluoperazine was able to stop the product of a gene called FOXO1 from being taken out of a tumor cell's nucleus.
Meanwhile, PC12 application of trifluoperazine does not the same effects on either of cytotoxicity or neurite outgrowth.
Besides matrix acidosis, the immunosuppressant cyclosporin A (16), its non-immunosuppressive analogues, N-methyl-valine cyclosporin and N-methylisoleucine cyclosporin (17), sanglifehrin A (18), bongkrekic acid (19), trifluoperazine (20), magnesium, certain ubiquinone analogues (21) as well as volatile anaesthetic agents (22) and propofol (23) have all been shown to either block the open state or prevent assembly of the mPTP, thus preventing both necrotic and apoptotic cell death.
In vitro antisecretory effects of trifluoperazine and other neuroleptics in rabbit and human small intestine.
The other most commonly prescribed drugs were (in order) risperidone, haloperidol, olanzapine, chlorpromazine, trifluoperazine, and quetiapine.
Drug Milligram equivalent to 20 Confidence mg of olanzapine (Zyprexa) Second generation antipsychotics Aripirazole (Abilify) 30 M Clozapine (Clozaril) 400 H Paliperidone (Invega) 9 M Quetiapine (Seroquel) 740 H Risperidone (Risperdal) 6 H First generation antipsychotics Haloperidol (Haldol) 10 H Perphenazine (Trilafon) 30 M Trifluoperazine (Stelazine) 20 M Key: H = high confidence level; M = moderate confidence level.
Cyclosporin A and trifluoperazine, two resistance-modulating agents, increase ivermectin neurotoxicity in mice.
Similarly, Alberto DiMascio contributed enormously to the study of the effects of different drug families such as anxiolytics (oxazepam, chlordiazepoxide), antidepressants (imipramine, desipramine), stimulants (d-amphetamine) and neuroleptics (chlorpromazine, promethazine, trifluoperazine, and perphenazine), among others, in both normal and pathological subjects (DiMascio, Klerman, Rinkel, Greenblatt & Brown 1958; DiMascio, Havens & Klerman, 1963a, 1963b; DiMascio & Buie, 1964; DiMascio, Heninger & Klerman, 1964; DiMascio, Klerman & Prusoff, 1975; DiMascio, Bernardo, Greenblatt & Marder, 1976).
1mM, trifluoperazine inhibited the hydrolysis of ATP and ADP in cucumber and rocket salad, and the hydrolysis of ATP, ADP and PPi in radish.
Here he remained until age 13, on thioridazine and trifluoperazine (doses unknown) when PPVT IQ of 55 led to transfer to a developmental center.
3%): the antipsychotic substances propericiazine, pipothiazine, trifluoperazine, fluphenazine, flupenthixol, zuclopenthixol, olanzapine, clozapine, loxapine, amisulpride, and risperidone and the antidepressant substances tianeptine, dosulepine, viloxazine, paroxetine, citalopram, venlafaxine, and sertraline.