tricyclic compound

tricyclic compound

[trīsik′lik]
Etymology: Gk, treis + kyklos, circle; L, componere, to put together
a chemical substance containing three rings in the molecular structure, especially a tricyclic antidepressant drug used in the treatment of reactive or endogenous depression. These drugs also have anticonvulsant, antihistaminic, anticholinergic, hypotensive, and sedative effects. See also antidepressant.
References in periodicals archive ?
Cidoxepin is the cis-isomer of the widely prescribed tricyclic compound doxepin.
Xanthones are biologically active molecules belonging to a class of tricyclic compounds characterized by a dibenzo-[gamma]-pyrone nucleus (Mazimba et al.
Far more effective for fibromyalgia - and most likely other central pain states as well - are dual reuptake inhibitors such as tricyclic compounds (amitriptyline, cyclobenzaprine), serotonin-norepinephrine reuptake inhibitors (milnacipran, duloxetine), gamma hydroxybutyrate, and gabapentin.
Far more effective for fibromyalgia--and most likely other central pain states as well--are dual reuptake inhibitors such as tricyclic compounds (amitriptyline, cyclobenzaprine), serotonin-norepinephrine reuptake inhibitors (milnacipran, duloxetine), gamma hydroxybutyrate, and gabapentin, he said.
The potential of antidepressant drugs to have cardiovascular toxicity manifested by arrhythmias and impairment of left ventricular systolic function is well known; this is found especially for tricyclic compounds and in the elderly patients with preexisting cardiovascular diseases.
In this light, it is notable that among PAHs with two to five rings, tricyclic compounds were the most potent in blocking dye coupling via gap junctions in an in vitro assay (Blaha et al.
One family of antidepressants called tricyclic compounds may give us more information.
Perhaps there's more of a connection between mood and a woman's risk for breast cancer rather than taking antidepressants alone, whether they're tricyclic compounds or other kinds.
Tricyclic compounds in which naphthalene is joined by "ortho fusion" with a hetercyclic compound.
Patent number 7,247,630 covers novel tricyclic compounds that regulate cytokines.