A benign tumor derived from outer root sheath epithelium of a hair follicle, consisting of cells with pale-staining cytoplasm containing glycogen; multiple trichilemmomas are present on the face in Cowden disease.
Synonym(s): tricholemmoma
[trichi- + G. lemma, husk, + -ōma, tumor]
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Partial biopsies of desmoplastic tricholemmoma may require distinction from basal cell carcinoma.
[1-4] Its features usually include facial tricholemmomas, acral and palmoplantar keratoses, multiple oral papules, and mucosal fibrosis with a cobblestone appearance.