trichoepithelioma

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trichoepithelioma

 [trik″o-ep″ĭ-the´leo´-mah]
a benign skin tumor originating in the follicles of the lanugo; it may occur as an inherited condition marked by multiple tumors (trichoepithelioma papillosum multiplex). Called also epithelioma adenoides cysticum.

trich·o·ep·i·the·li·o·ma

(trik'ō-ep'i-thē'lē-ō'mă), [MIM*132700]
Multiple small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts; autosomal dominant inheritance.
[tricho- + epithelioma]

trichoepithelioma

/tricho·epi·the·li·o·ma/ (-ep″ĭ-the″le-o´mah) a benign skin tumor originating in the follicles of the lanugo, usually on the face; it may occur as an inherited condition marked by multiple tumors (multiple t.) but also may occur as a noninherited solitary lesion (solitary t.) .

trichoepithelioma

[trik′ō·ep′ithē′lē·ō′mə] pl. trichoepitheliomas, trichoepitheliomata
Etymology: Gk, thrix + epi, above, thele nipple, oma, tumor
a cutaneous tumor derived from the basal cells of the follicles of fine body hair. One form of trichoepithelioma is an inherited condition and usually occurs as multiple growths. Also called acanthoma adenoides cysticum, epithelioma adenoides cysticum.
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Trichoepithelioma

trich·o·ep·i·the·li·o·ma

(trik'ō-ep'i-thē'lē-ō'mă)
Any of numerous small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts.
Synonym(s): Brooke tumor.

Brooke,

Henry Ambrose Grundy, English dermatologist, 1854-1919.
Brooke disease - (1) multiple small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts. Synonym(s): Ancell-Spiegler cylindroma; Ancell-Spiegler syndrome; Ancell syndrome; Brooke epithelioma; Brooke-Fordyce disease; Brooke-Fordyce trichoepithelioma; Brooke-Spiegler phatomatosis; Brooke tumor; trichoepithelioma - (2) a rare condition simulating keratosis follicularis. Synonym(s): Morrow-Brooke syndrome
Brooke epithelioma - Synonym(s): Brooke disease (1)
Brooke-Fordyce disease - Synonym(s): Brooke disease (1)
Brooke-Fordyce trichoepithelioma - Synonym(s): Brooke disease (1)
Brooke tumor - Synonym(s): Brooke disease (1)
Morrow-Brooke syndrome - Synonym(s): Brooke disease (2)

trich·o·ep·i·the·li·o·ma

(trik'ō-ep'i-thē'lē-ō'mă) [MIM*132700]
Any of numerous small benign nodules, occurring mostly on the face, derived from basal cells of hair follicles enclosing small keratin cysts.
Synonym(s): Brooke tumor.
[tricho- + epithelioma]

trichoepithelioma

a benign skin tumor originating in the keratinocytes of the hair follicle outer sheath or the hair matrix. It occurs as single or sometimes multiple, firm, rounded skin nodules that may ulcerate. They are common in dogs, particularly Cocker spaniels. Called also epithelioma adenoides cysticum.
References in periodicals archive ?
The benign, hair-germ tumors trichoblastoma (TB) and trichoepithelioma (TE) most commonly arise on the head and neck.
Desmoplastic trichoepithelioma (DTE) is a histologic variant of TE that merits additional description.
Multiple familial trichoepithelioma (MFT) is also called as epithelioma adenoids cysticum and Brooke-Fordyce trichoepitheliomas.
Multiple trichoepitheliomas in a mother and daughter.
The Rombo syndrome: a familial disorder with vermiculate atrophoderma, milia, hypotrichosis, trichoepitheliomas, basal cell carcinomas and peripheral vasodilation with cyanosis.
35,39) Androgen receptor reactivity has also been noted in classic or conventional trichoepitheliomas.
Hereditary Tumor Syndromes Associated With Cutaneous Nodules Syndrome Mode of Genetic Defect Inheritance Muir-Torre syndrome Autosomal Defective mismatch repair dominant genes hMLH1 and hMSH2 in 70% Gardner syndrome Autosomal APC gene mutations (5q21) (phenotypic variant of dominant FAP) Cowden syndrome (multiple Autosomal PTEN gene mutations hamartoma syndrome) dominant (10q23) Multiple trichoepitheliomas Autosomal CYLD gene mutations (possible phenotypic dominant (16q12-13) variant of Brooke-Spiegler syndrome) Basal cell nevus syndrome Autosomal PTCH gene mutations (Goltz syndrome) dominant (9q22.
On thorough PubMed search we found a case of acral syringomas associated with carcinoid syndrome13 and trichoepithelioma.
Patients may also develop facial trichoepitheliomas, eccrine spiradenomas, and milia, with highly variable expressivity.
Rarely, syringoma may be associated with the Brooke-Spiegler syndrome, an autosomal dominant disease characterized by the development of multiple cylindromas, trichoepitheliomas, and occasional spiradenomas.
Multiple cylindromas accompanied by spiradenomas or trichoepitheliomas or both are found in inherited syndromes, such as Brooke-Spiegler syndrome, familial cylindromatosis, and multiple familial trichoepithelioma syndrome.
Mutations in this pathway have been implicated in numerous abnormalities including NBCCS, sporadic basal cell carcinomas, trichoblastomas, trichoepitheliomas (TEs), cylindromas, nevus sebaceous, and dentigous cysts.