trichlorfon


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metrifonate

 [met″rĭ-fo´nāt]
an organophosphorous compound having potent anticholinesterase activity; used topically against ectoparasites and internally as an anthelmintic, especially effective against Schistosoma haematobium.

tri·chlor·fon

(trī-klōr'fon),
An organophosphorus compound effective against immature and mature stages of Schistosoma haematobium, but ineffective against other species of Schistosoma in humans.
Synonym(s): metrifonate

trichlorfon

[tri-klor′fon]
metrifonate. Also spelled trichlorphon.

metrifonate

An organophosphate that is an irreversible inhibitor of acetylcholinesterase. Metrifonate had some currency for treating Schistosoma haematobium schistosomiasis, but proved less effective than praziquantel and is thus no longer used for this indication. It was being developed for Alzheimer's dementia, but was withdrawn due to adverse effects (respiratory paralysis and defects in neuromuscular transmission).

trichlorfon

an organophosphorus insecticide and anthelmintic, used in horses, often in combination with other anthelmintics, for treatment of endoparasites and cutaneous habronemiasis. Also used in dogs against whipworms and as a pour-on in cattle for control of warble flies. It is used in fishponds and commercial fish farms to control anchorworms, gill flukes and lice. Called also metrifonate.

trichlorphon, trichlorfon

an organophosphorus compound used as an anthelmintic. It is toxic for sheep at recommended dose rates and is also hazardous for cattle. In pregnant sows it causes congenital cerebellar agenesis in the piglets and has been associated with left laryngeal hypoplasia in young horses. A solution of the compound is unstable and should be discarded if not used on the same day as the metabolite is toxic.
References in periodicals archive ?
Screening of insecticides showed that all of the carbamatesand the OPs malathion, parathion and diazinon gave stronginhibition while other OPs such as trichlorfon, acephate anddimethoate showed less than 50% inhibition to AChE activity (Fig.
Examples of pesticide active ingredients responsible for poisoning Organophosphates Methyl parathion Ethal parathion Malathion Diazinon Fenthion Dichlorvos Chlorpyrifos Trichlorfon Anticoagulants Brodifacoum Difethialone Chlorofacinone Coumachlor Difenacoum Diphacinone Warfarin Pyrethroids Allethrin Bifenthrin Cypermeter Permethrin Deltamethrin Organochlorines Lindane (lice shampoo) Carbamates Aldicarb Carbofuran Oxamyl Methomyl Formetanate Methiocarb Aminocarb Mecarbam Bendiocarb Propoxur Herbicides Glysophate Atrazine Nicosulfuran Fenoxaprop Alachlor Pendimethalin Halosulfuran-methyl Paraquat Triclopyr Clopyralid Picloram N,N-diethyl-meta-toluamide (DEET- mosquito repellent)
insecticide Active Month applications ingredients POPULATION collected in 2006 used (3) P Aug 11 Bifenthrin Trichlorfon BH Aug 11 Bifenthrin Carbaryl imidacloprid Trichlorfon JC Jun 8 Bifenthrin Permethrin Carbaryl Trichlorfon Acephate V (1) Jul 4 Bifenthrin Cypermethrin GE12 (1) Jul 4 Bifenthrin Cypermethrin LF Jul 3 Bifenthrin Cypermethrin FS (2) Jul 3 Bifenthrin Cypermethrin L (2) Jul unknown BP May 2 Bifenthrin CT Jun 5 Bifenthrin PC May unknown SCL Jul unknown DAL Jul 1 Bifenthrin (4) DAR Jul 1 Clothianidin (5) HF Jun-Aug 0 -- GE18 (1) Jul 0 -- (1) Denotes populations in the same neighborhood.
Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additives Series 45: Trichlorfon (2000).
Histopathologic changes in the kidney tissue of Prochilodus lineatus Valenciennes, 1836 (Characiformes, Prochilodontidae) induced by sublethal concentration of trichlorfon exposure.
The strongest relationship was found for a chemical called trichlorfon, with an 85 percent increase in diabetes risk for frequent and infrequent users and a nearly 250 percent increase in risk for those who used the chemical more than 10 times.
1] Etofenprox 0,3 [+ o -] 0,09 Ba 0,1 [+ o -] 0,06 Bb Fenitrothion 0,0 [+ o -] 0,00 Ba 0,0 [+ o -] 0,00 Ba Methidathion 0,0 [+ o -] 0,0 Ba 0,0 [+ o -] 0,00 Ba Trichlorfon 0,4 [+ o -] 0,09 Ab 0,7 [+ o -] 0,05 Aa Testemunha 0,4 [+ o -] 0,07 Ab 0,5 [+ o -] 0,06 Aa Cy (%) 8,11 Geracao [F.
For example, trichlorfon is stable for over eighty hours in a spray tank with water that has a pH of 6.
From 1972, rice producers implemented insecticide sprayings with fenitrothion, trichlorfon, and chlorphenamidine, which were conducted at the end of July each year, to control this pest (Table).