A condition known as imposex where the females grow a pseudopenis and become reproductively nonviable is believed to result from tributyltin
exposure (O'Neal et al.
Metal biocides, such as tributyltin
(TBT) and copper are added to marine paints as antifouling compounds.
In rats, EDCs such as tributyltin
(TBT) (Chamorro-Garcia et al.
In the late 1950s, new properties of organotin compounds were discovered, particularly for tributyltin
(TBT), allowing its use as an agent to avoid the adherence of these organisms (Furdek et al., 2012).
(3) Some of the well-recognized and extensively studied obesogens include phthalates, bisphenols, PCBs, PBDEs, tributyltin
, dioxins, DDT and DDE, nonylphenol and parabens.
Diet samples in some of the studies showed, for example, that obesogens such as tributyltin
- a chemical in anti-fouling paint banned a decade ago, and cadmium - a metal widespread in the environment associated with certain cancers, can still be found in food products, in some cases at high concentrations.
Of the original 75 NTP80 collection compounds, the following four had to be removed from physicochemical analyses because they are salts or contain metallic elements not supported by our methods: (i) methylmercury (II) chloride (MeHgCl), (ii) acetic acid manganese (2+) salt, (iii) bis(tributyltin
)oxide and (iv) methylcyclopentadienyl manganese tricarbonyl.
Antifouling product type contain toxic biocidal compounds such as copper, zinc and tributyltin
(TBT) which gradually leach into the water to prevent formation of fouls in boats.
Brain cytochrome P450 aromatase gene isoforms and activity levels in atlantic salmon after waterborne exposure to nominal environmental concentrations of the pharmaceutical ethynylestradiol and antifoulant tributyltin
Orally administered tributyltin
(TBT) can significantly increase the FE through inhibiting feed intake in mice .
(TBT) could activate all three types of RXR (retinoid X receptor): PPAR[alpha], PPAR[beta]/[delta], and PPAR[gamma] heterodimers by PPRE luciferase experiment .