triazole


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triazole

 [tri´ah-zōl, tri-a´zōl]
1. an organic compound in which three atoms of the five that make up the ring are nitrogen atoms.
2. any of a class of antifungal agents that contain this compound.

triazole

(trī'a-zōl),
Member of a series of heterocyclic compounds containing three nitrogen atoms in the azole group; also used to describe of of a group of antifungal agents (e.g., itraconazole) in this chemical class.

triazole

/tri·a·zole/ (tri´ah-zōl) (tri-a´zōl)
1. a five-membered heterocyclic ring containing two carbon and three nitrogen atoms.
Triazole.
2. any of a class of antifungal compounds containing this structure.

triazole

[tri′ah-zōl, tri-a′zōl]
1 an organic compound in which three atoms of the five that make up the ring are nitrogen atoms.
2 any of a class of antifungal agents that contain this compound.
References in periodicals archive ?
An insight to the synthetically obtained triazole possessing numerous biological activities.
This study was carried out to retrieve data pertaining to triazole resistance using the Scopus search engine.
A new triazole, voriconazole (UK-109,496), blocks sterol biosynthesis in Candida albicans and Candida krusei.
Triazole, with its preventive and post infection curative property has higher consumption as compared to other fungicides available worldwide.
We were intending to complete the programme with a mixed triazole T3 ear wash in early June but, with the weather becoming so changeable, we added an extra early July dose of tebuconazole as insurance against the fusarium we need to keep out of seed crops at all costs," Horsburgh added.
An invisible threat: mutation-mediated resistance to triazole drugs in Aspergillus.
3] Fluconazole is a triazole antifungal agent commonly used in the treatment of dermatophytic and candidal infections with side effects such as nausea and liver enzyme elevations.
The triazole fungicides tebuconazole and ciproconazole are used in Brazilian viticulture mainly to control powdery mildew and ripe rot, and strobilurin fungicides azoxystrobin and pyraclostrobin are used mainly to control downy mildew and to a lesser extent powdery mildew and ripe rot.
Similarly, treatment of 2 with 3-amino-5-carboxy-1, 2 4- triazole (3b) gave 4-(5-carboxy-1, 2, 4-triazolyl-3amino)-3-nitro-2H-[1]-benzopyran-2-one (4b).
Part II then discusses synthesis and particular mimetic molecules in more detail, including bioisosteres, solid-phase synthesis, combinatorial approaches, click chemistry with triazole scaffolding, peptoids, sugar amino acids as scaffolds, cyclic alpha-amino acids as proline mimics, beta-turn mimetics, and foldamers, including material on both structure-function relationships and synthesis.
Heating induces crosslinking by 1,3 dipolar cycloaddition between an azide and an alkyne to give a 1,3 triazole linkage, resulting in a very stable structure.