triamcinolone


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

triamcinolone

 [tri″am-sin´o-lōn]
a prednisolone derivative used in replacement therapy for adrenocortical insufficiency and as an antiinflammatory and immunosuppressant in a wide variety of disorders; administered orally in the form of the acetonide, diacetate, and hexacetonide esters.

triamcinolone

(trī′ăm-sĭn′ə-lōn′)
n.
A synthetic glucocorticoid, C21H27FO6, used, usually in acetal or acetate forms, in the treatment of a wide variety of inflammatory and allergic conditions.

triamcinolone

A CORTICOSTEROID drug used to treat inflammatory disorders, ASTHMA, THROMBOCYTOPENIA and some forms of LEUKAEMIA. Brand names are Adcortyl, Adcortyl in Orabase, Kenalog, Lederspan and Nasacort. Triamcinolone is also an ingredient is a range of preparations for external use.

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.

chalazion 

A chronic inflammatory lipogranuloma due to retention of the secretion (such as blocked ducts) of a meibomian gland in the tarsus of an eyelid. It is characterized by a gradual painless swelling of the gland without marked inflammatory signs and sometimes astigmatism which is induced by the cyst pressing on the cornea (Fig. C5). Small chalazia may disappear spontaneously but large ones usually have to be incised and curetted (i.e. removal of the pus with a scraper) through a tarsal incision. Resolution may also occur after local injection of a corticosteroid drug (e.g. dexamethasone or triamcinolone). Syn. meibomian cyst (although it is not a true cyst because its walls are made of granulomatous tissue and not lined with epithelium). See internal hordeolum.
Fig. C5 Upper eyelid chalazionenlarge picture
Fig. C5 Upper eyelid chalazion
References in periodicals archive ?
Recently, our group reported on the pharmacokinetics of lumbar epidural-administered triamcinolone [7].
Further subconjunctival triamcinolone (4mg/0.1mL x 0.5mL) was injected inferiorly in each eye.
Twenty-five years later, intravitreal triamcinolone showed no long-term benefit in VA improvement; thus, laser continued to be the first-line treatment option for DME.
Intravitreal injection of triamcinolone for diffuse macular oedema.
Wiggins's use of triamcinolone was revealed when the Fancy Bears hackers published medical data stored by the World Anti-Doping Agency (WADA) on their site last week.
In one group, the patients were given an intravitreal injection of bevacizumab 1.25 mg/0.05 mL (Avastin[R]), while the second group patients were administered a triamcinolone acetonid injection 4 mg/0.1 mL (Kenalog[R]).
These trials tested different doses of all drugs except triamcinolone and flunisolide.
1) right grinding of mandibular incisal edges central and incisors triamcinolone application Case 2 Natal left and Negative Extraction and right triamcinolone mandibular application central incisors Case 3 Natal left Positive Selective (Fig.
One case-control study was conducted for each fungal species outbreak (Fusarium infections associated with Franck's BBG administered during vitrectomies and Bipolaris infections associated with Franck's triamcinolone injected intravitreally); only species-confirmed cases (i.e., cases confirmed by culture) were included.
But, two interventional case series have demonstrated that posterior juxtascleral infusion of a viscoelastic formulation of triamcinolone acetonide is an effective treatment for diffuse diabetic macular edema (DME) unresponsive to laser photocoagulation [23, 24].
(Nasdaq: CLSD), a biopharmaceutical company dedicated to developing and delivering treatments that restore and preserve vision for people with serious back of the eye diseases, announced today an update regarding the Company's 505(b)(2) New Drug Application (NDA) for XIPERETM (triamcinolone acetonide suprachoroidal injectable suspension) with the U.S.