For respiratory disease a trial of therapy
is indicated if there are prominent symptoms, progression of disease or lack of remission over 6 months follow-up.
Cirrhotic patients with significant inflammation, on the other hand, might benefit from a 3- to 6-month trial of therapy
to slow down progression, he said adding: "That's really a decision for a hepacologist to make."
Even in this group, a trial of therapy
with 200 mg of ferrous iron is more correctly recommended for 3 weeks prior to review for response, as opposed to the 2 months, as suggested by the authors.
Providers should base the decision to initiate a trial of therapy
with a cholinesterase inhibitor or memantine on individualized assessment.
They discuss with the family the imprecise nature of diagnosis, (1) risks vs benefits of therapy, and start an 8-week trial of therapy
. If the family notes improvement (or stabilization), treatment can be continued.
Enzyme potentiated desensitization: A sixteen month trial of therapy
with 134 patients.
counts greater than 5 million/ml) should be given a trial of therapy
Although BPPV has a benign long-term outcome, it can be quite bothersome to patients and I have always felt compelled to offer some trial of therapy
. Given the overall success and the relative safety of otolith repositioning maneuvers, such as the Epley maneuver, it has become my practice to refer patients to a physical therapist or other provider trained in these techniques.
Some patients with statin-induced myopathies also may respond to a trial of therapy
with coenzyme Q10 at a dose of 60 mg b.i.d., he noted.