The majority of individuals with cases of CNS involvement are able to successfully clear or control the treponeme
That's the implication of the first study to probe the genetic makeup and evolutionary relationships of strains of bacteria, known as treponemes
, that cause syphilis and related diseases.
7) During this stage, treponemes
invade the central nervous system, heart, bone, and skin, triggering vigorous host cellular immune responses and delayed-type hypersensitivity reactions.
are highly infectious and saprophytic treponemes
can be found on mucous membranes in the mouth, genital tract and also in skin ulcers.
Although serological and microbiological treatment failures have been reported following [benzathine penicillin G] treatment," observe STI experts David Lewis (National Institute for Communicable Diseases, South Africa) and Sheila Lukehart (University of Washington, Seattle), "these may be due to sequestration of treponemes
protected in the central nervous system or to reinfection.
Inprimary syphilis, the chancre teems with treponemes
that can be seen with darkfield microscopy.
Some experts consider screening blood from volunteer donors for syphilis antibodies to be unnecessary in light of declining syphilis rates and the belief that the processing and refrigeration of blood and blood products would destroy the treponemes
A real-time duplex PCR targeting the DNA polymerase I gene (polA, tp0105) of pathogenic treponemes
(which detects all 3 T.
Thelocalisation of treponemes
and characterisation of the inflammatory infiltrate in skin biopsies from patients with primary or secondary syphilis, or early infectious yaws.
Other people's afflicted mouths instead support large populations of hydrogen-consuming bacteria called treponemes
CDC recommends that all children from areas where treponemes
are known to be endemic be considered for screening by Rapid Plasma Reagin or Venereal Disease Research Laboratory tests at the initial health screening.
7) TP-specific staining of histologic specimens may also be performed, but sensitivity is diminished if concentration of treponemes