trephine biopsy


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Related to trephine biopsy: Bone marrow aspiration

punch bi·op·sy

any method that removes a small cylindric specimen for biopsy by means of a special instrument that pierces the organ directly, or through the skin, or a small incision in the skin.
Synonym(s): trephine biopsy

trephine biopsy

Hematology A BM Bx collected using a Jamshidi needle
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Trephine biopsy sections showed diffuse and interstitial infiltration by blast cells in all the cases.
Bone Marrow Trephine Biopsy showing Complete Replacement of Normal Elements by Plasma Cells (Packed Type) 40X
Bone marrow aspiration and trephine biopsy findings were consistent with a diagnosis of severe aplastic anemia (marrow cellularity=20% for age; Figure 2a-g).
Bone marrow trephine biopsy is important in identifying marrow involvement for treatment purpose.
Although paratrabecular location is one of the features that historically has been strongly suggestive of malignancy even on a stand-alone basis, 6 of 85 reactive cases with trephine biopsy sections in our study (7%) contained aggregates with a paratrabecular location.
8% of the cases the bone marrow aspiration and trephine biopsy showed same diagnosis i.
A tissue biopsy is necessary to demonstrate plasma cells, and a bone marrow aspirate and trephine biopsy should demonstrate no clonal plasma cells.
With this information it is logical to directly examine the bone marrow by means of aspiration coupled with trephine biopsy (Fig.
Their approach is based on the integrated assessment of peripheral blood and bone marrow aspirate films, trephine biopsy sections, and supplementary investigations, and includes discussion of the clinical context of bone marrow diagnosis and cytological and histological features.
Bone marrow trephine biopsy showed 50-60% cellularity, dominated by normal erythropoiesis but with a paratrabecular lymphoid infiltration with [lambda]-clonal, CD20+ cells showing plasmacytoid differentiation.
CBC and biochemistry, whole-body CT, lumbar puncture, bone marrow aspirate, and trephine biopsy findings were all normal.